Gap finder

Search review questions

Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Every word you type has to appear somewhere in the question, and the closest matches are ranked first.

Limit to evidence status or GRADE (optional)

75,239 questions in 5,342 reviews

current versions
No studies 15,213 · 20.2%Ungraded 10,323 · 13.7%Very low 17,528 · 23.3%Low 17,951 · 23.9%Moderate 11,190 · 14.9%High 3,034 · 4%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

QuestionEffectEvidenceStatus / GRADE
One type of coverall vs another type of coverall
CI: confidence interval. · asbestos workers
Personal protective equipment for preventing asbestos exposure in workers (2024) · Cochrane
no estimate extractedNRNo studies
Full‐face filtering masks vs no respiratory protection
Asbestos exposure after doffing · asbestos workers
Personal protective equipment for preventing asbestos exposure in workers (2024) · Cochrane
no estimate extractedNRNo studies
Full‐face filtering masks vs no respiratory protection
Donning and doffing errors · asbestos workers
Personal protective equipment for preventing asbestos exposure in workers (2024) · Cochrane
no estimate extractedNRNo studies
Full‐face filtering masks vs no respiratory protection
Adverse effects · asbestos workers
Personal protective equipment for preventing asbestos exposure in workers (2024) · Cochrane
no estimate extractedNRNo studies
Full‐face filtering masks vs no respiratory protection
CI: confidence interval. · asbestos workers
Personal protective equipment for preventing asbestos exposure in workers (2024) · Cochrane
no estimate extractedNRNo studies
Supplied air respirators vs no respiratory protection
Reduction in exposure to asbestos · asbestos workers
Personal protective equipment for preventing asbestos exposure in workers (2024) · Cochrane
no estimate extractedNRModerate
Supplied air respirators vs no respiratory protection
Asbestos exposure after doffing · asbestos workers
Personal protective equipment for preventing asbestos exposure in workers (2024) · Cochrane
no estimate extractedNRNo studies
Supplied air respirators vs no respiratory protection
Donning and doffing errors · asbestos workers
Personal protective equipment for preventing asbestos exposure in workers (2024) · Cochrane
no estimate extractedNRNo studies
Supplied air respirators vs no respiratory protection
Adverse effects · asbestos workers
Personal protective equipment for preventing asbestos exposure in workers (2024) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Off‐midline closure vs conventional midline closure
Time to wound healing · pilonidal sinus
Midline and off‐midline wound closure methods after surgical treatment for pilonidal sinus (2024) · Cochrane
no estimate extracted3 studies · 300 participantsModerate
Summary of findings table ‐ Off‐midline closure vs tension‐free midline closure
Recurrence rate · pilonidal sinus
Midline and off‐midline wound closure methods after surgical treatment for pilonidal sinus (2024) · Cochrane
RR 0.69 [0.3, 1.61]6 studies · 551 participantsVery low
Summary of findings table ‐ Off‐midline closure vs tension‐free midline closure
Wound infection · pilonidal sinus
Midline and off‐midline wound closure methods after surgical treatment for pilonidal sinus (2024) · Cochrane
RR 0.44 [0.16, 1.17]6 studies · 559 participantsVery low
Summary of findings table ‐ Off‐midline closure vs tension‐free midline closure
Wound dehiscence · pilonidal sinus
Midline and off‐midline wound closure methods after surgical treatment for pilonidal sinus (2024) · Cochrane
RR 0.82 [0.17, 3.84]3 studies · 250 participantsVery low
Summary of findings table ‐ Off‐midline closure vs tension‐free midline closure
Time to return to work · pilonidal sinus
Midline and off‐midline wound closure methods after surgical treatment for pilonidal sinus (2024) · Cochrane
no estimate extracted1 study · 60 participantsLow
Summary of findings table ‐ Off‐midline closure vs tension‐free midline closure
Quality of life ‐ not reported · pilonidal sinus
Midline and off‐midline wound closure methods after surgical treatment for pilonidal sinus (2024) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Off‐midline closure (Karydakis flap) vs off‐midline closure (Limberg flap)
Time to wound healing · pilonidal sinus
Midline and off‐midline wound closure methods after surgical treatment for pilonidal sinus (2024) · Cochrane
no estimate extracted6 studies · 526 participantsModerate
Summary of findings table ‐ Off‐midline closure (Karydakis flap) vs off‐midline closure (Limberg flap)
Proportion of wounds healed · pilonidal sinus
Midline and off‐midline wound closure methods after surgical treatment for pilonidal sinus (2024) · Cochrane
RR 1.2 [0.77, 1.86]1 study · 30 participantsLow
Summary of findings table ‐ Off‐midline closure (Karydakis flap) vs off‐midline closure (Limberg flap)
Recurrence rate · pilonidal sinus
Midline and off‐midline wound closure methods after surgical treatment for pilonidal sinus (2024) · Cochrane
RR 1.14 [0.61, 2.14]9 studies · 890 participantsLow
Summary of findings table ‐ Off‐midline closure (Karydakis flap) vs off‐midline closure (Limberg flap)
Wound infection · pilonidal sinus
Midline and off‐midline wound closure methods after surgical treatment for pilonidal sinus (2024) · Cochrane
RR 1.55 [0.9, 2.68]8 studies · 869 participantsLow
Summary of findings table ‐ Off‐midline closure (Karydakis flap) vs off‐midline closure (Limberg flap)
Wound dehiscence · pilonidal sinus
Midline and off‐midline wound closure methods after surgical treatment for pilonidal sinus (2024) · Cochrane
RR 1.2 [0.41, 3.5]7 studies · 776 participantsLow
Summary of findings table ‐ Off‐midline closure vs conventional midline closure
Proportion of wounds healed · pilonidal sinus
Midline and off‐midline wound closure methods after surgical treatment for pilonidal sinus (2024) · Cochrane
RR 1.13 [0.92, 1.39]2 studies · 207 participantsVery low
Summary of findings table ‐ Off‐midline closure (Karydakis flap) vs off‐midline closure (Limberg flap)
Time to return to work · pilonidal sinus
Midline and off‐midline wound closure methods after surgical treatment for pilonidal sinus (2024) · Cochrane
no estimate extracted6 studies · 541 participantsLow
Summary of findings table ‐ Off‐midline closure (Karydakis flap) vs off‐midline closure (Limberg flap)
Quality of life ‐ not reported · pilonidal sinus
Midline and off‐midline wound closure methods after surgical treatment for pilonidal sinus (2024) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Off‐midline closure vs conventional midline closure
Recurrence rate · pilonidal sinus
Midline and off‐midline wound closure methods after surgical treatment for pilonidal sinus (2024) · Cochrane
RR 0.22 [0.11, 0.45]13 studies · 1492 participantsModerate
Summary of findings table ‐ Off‐midline closure vs conventional midline closure
Wound infection · pilonidal sinus
Midline and off‐midline wound closure methods after surgical treatment for pilonidal sinus (2024) · Cochrane
RR 0.32 [0.22, 0.49]13 studies · 1568 participantsModerate
Summary of findings table ‐ Off‐midline closure vs conventional midline closure
Wound dehiscence · pilonidal sinus
Midline and off‐midline wound closure methods after surgical treatment for pilonidal sinus (2024) · Cochrane
RR 0.44 [0.27, 0.71]11 studies · 1389 participantsLow
Summary of findings table ‐ Off‐midline closure vs conventional midline closure
Time to return to work · pilonidal sinus
Midline and off‐midline wound closure methods after surgical treatment for pilonidal sinus (2024) · Cochrane
no estimate extracted6 studies · 820 participantsLow
Summary of findings table ‐ Off‐midline closure vs conventional midline closure
Quality of life ‐ not reported · pilonidal sinus
Midline and off‐midline wound closure methods after surgical treatment for pilonidal sinus (2024) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Off‐midline closure vs tension‐free midline closure
Time to wound healing · pilonidal sinus
Midline and off‐midline wound closure methods after surgical treatment for pilonidal sinus (2024) · Cochrane
no estimate extracted1 study · 116 participantsLow
Summary of findings table ‐ Off‐midline closure vs tension‐free midline closure
Proportion of wounds healed · pilonidal sinus
Midline and off‐midline wound closure methods after surgical treatment for pilonidal sinus (2024) · Cochrane
RR 1.24 [1.06, 1.46]1 study · 115 participantsLow
Favipiravir vs no treatment, supportive treatment, or other antiviral treatment
All‐cause mortality – at 28 to 30 days, or in‐hospital · people with confirmed COVID‐19
Favipiravir for treating COVID‐19 (2024) · Cochrane
RR 0.84 [0.49, 1.46]11 studies · 3459 participantsVery low
Favipiravir vs no treatment, supportive treatment, or other antiviral treatment
Progression to invasive mechanical ventilation · people with confirmed COVID‐19
Favipiravir for treating COVID‐19 (2024) · Cochrane
RR 0.86 [0.68, 1.09]8 studies · 1383 participantsVery low
Favipiravir vs no treatment, supportive treatment, or other antiviral treatment
Need for admission to hospital (if ambulatory) · people with confirmed COVID‐19
Favipiravir for treating COVID‐19 (2024) · Cochrane
RR 1.04 [0.44, 2.46]4 studies · 670 participantsLow
Favipiravir vs no treatment, supportive treatment, or other antiviral treatment
Time to clinical improvement (defined as time to a 2‐point reduction in patients’ admission status on WHO’s ordinal scale) · people with confirmed COVID‐19
Favipiravir for treating COVID‐19 (2024) · Cochrane
HR 1.13 [0.69, 1.83]4 studies · 721 participantsVery low
Favipiravir vs no treatment, supportive treatment, or other antiviral treatment
Progression to oxygen therapy · people with confirmed COVID‐19
Favipiravir for treating COVID‐19 (2024) · Cochrane
RR 1.2 [0.83, 1.75]2 studies · 543 participantsLow
Favipiravir vs no treatment, supportive treatment, or other antiviral treatment
All adverse events · people with confirmed COVID‐19
Favipiravir for treating COVID‐19 (2024) · Cochrane
RR 1.27 [1.05, 1.54]18 studies · 4699 participantsLow
Favipiravir vs no treatment, supportive treatment, or other antiviral treatment
Serious adverse events attributable to the drug · people with confirmed COVID‐19
Favipiravir for treating COVID‐19 (2024) · Cochrane
RR 1.04 [0.76, 1.42]12 studies · 3317 participantsLow
Summary of findings table ‐ Vitamin A supplements vs placebo
Incidence of acute URTIs during the study period (the number of acute URTIs over a period of time) · children up to the age of 7 at risk of upper respiratory tract infection
Oral vitamin A supplements to prevent acute upper respiratory tract infections in children up to seven years… (2024) · Cochrane
RR 1 [0.92, 1.09]3 studies · 22668 participantsLow
Summary of findings table ‐ Vitamin A supplements vs placebo
Incidence of acute URTIs during the study period (proportion of participants with an acute URTI) · children up to the age of 7 at risk of upper respiratory tract infection
Oral vitamin A supplements to prevent acute upper respiratory tract infections in children up to seven years… (2024) · Cochrane
no estimate extracted2 studies · 15535 participantsLow
Summary of findings table ‐ Vitamin A supplements vs placebo
Adverse events · children up to the age of 7 at risk of upper respiratory tract infection
Oral vitamin A supplements to prevent acute upper respiratory tract infections in children up to seven years… (2024) · Cochrane
no estimate extracted1 study · 116 participantsVery low
Summary of findings table ‐ Vitamin A supplements vs placebo
Severity of subjective symptoms (mean duration of acute URTI) · children up to the age of 7 at risk of upper respiratory tract infection
Oral vitamin A supplements to prevent acute upper respiratory tract infections in children up to seven years… (2024) · Cochrane
no estimate extracted2 studies · 290 participantsVery low
Summary of findings table ‐ Vitamin A supplements vs placebo
Time to occurrence of acute URTI ‐ not reported · children up to the age of 7 at risk of upper respiratory tract infection
Oral vitamin A supplements to prevent acute upper respiratory tract infections in children up to seven years… (2024) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Vitamin A supplements vs placebo
Number of cases with complications ‐ not reported · children up to the age of 7 at risk of upper respiratory tract infection
Oral vitamin A supplements to prevent acute upper respiratory tract infections in children up to seven years… (2024) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Vitamin A supplements vs placebo
Rate of hospitalisation ‐ not reported · children up to the age of 7 at risk of upper respiratory tract infection
Oral vitamin A supplements to prevent acute upper respiratory tract infections in children up to seven years… (2024) · Cochrane
no estimate extractedNRNo studies
Dietary interventions vs control
BMI short‐term (12 weeks from baseline to < 9 months) · children aged 5 to 11 years
Interventions to prevent obesity in children aged 5 to 11 years old (2024) · Cochrane
no estimate extracted5 studies · 2107 participantsLow
Activity interventions vs control
BMI long‐term (> 15 months) · children aged 5 to 11 years
Interventions to prevent obesity in children aged 5 to 11 years old (2024) · Cochrane
no estimate extracted8 studies · 8302 participantsLow
Activity interventions vs control
zBMI short‐term (12 weeks from baseline to < 9 months) · children aged 5 to 11 years
Interventions to prevent obesity in children aged 5 to 11 years old (2024) · Cochrane
no estimate extracted6 studies · 3580 participantsLow
Activity interventions vs control
zBMI medium‐term (9 months to < 15 months) · children aged 5 to 11 years
Interventions to prevent obesity in children aged 5 to 11 years old (2024) · Cochrane
no estimate extracted13 studies · 20600 participantsModerate
Activity interventions vs control
zBMI long‐term (> 15 months) · children aged 5 to 11 years
Interventions to prevent obesity in children aged 5 to 11 years old (2024) · Cochrane
no estimate extracted6 studies · 6940 participantsLow
Activity interventions vs control
Serious adverse events · children aged 5 to 11 years
Interventions to prevent obesity in children aged 5 to 11 years old (2024) · Cochrane
no estimate extracted11 studies · 21278 participantsLow