Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,733 questions · 1,794 findings · 326 reviews · Headline outcomes only

No studies found 243 · 13.5%GRADE not reported 96 · 5.4%Very low 597 · 33.3%Low 506 · 28.2%Moderate 303 · 16.9%High 49 · 2.7%

Psychological therapies vs SSRI

Short‐term improvement Scale used (range; lower is better): panic frequency Clinical Global Impression (1 to 7) Agoraphobic Cognitive Questionnaire (1 to 70) Fear Questionnaire Agoraphobia Subscale (0 to 14) · adults with panic disorder
1 finding from 1 review

Intervention not reported

Short‐term mortality · people with necrotising pancreatitis

The review found no eligible studies for this question.

1 finding from 1 review

Laparoscopic vs open transhiatal oesophagectomy

Short‐term mortality (in hospital or within 3 months) · patients with oesophageal cancer

It is very uncertain whether laparoscopic changes short‐term mortality (in hospital or within 3 months) compared with open transhiatal oesophagectomy (very low certainty).

1 finding from 1 review

Intervention not reported

Short‐term mortality · patients with pancreatic pseudocysts

The review found no eligible studies for this question.

1 finding from 1 review

Non‐surgical vs surgical treatment of oesophageal cancer (primary outcomes)

Short‐term mortality All‐cause mortality either in‐hospital or within 3 months · patients with oesophageal cancer

It is very uncertain whether non‐surgical changes short‐term mortality All‐cause mortality either in‐hospital or… compared with surgical treatment of oesophageal cancer (primary outcomes) (very low certainty).

1 finding from 1 review

Duodenum‐preserving pancreatic resection vs pancreaticoduodenectomy

Short‐term mortality · people requiring surgery for chronic pancreatitis

It is very uncertain whether duodenum‐preserving pancreatic resection changes short‐term mortality compared with pancreaticoduodenectomy (very low certainty).

1 finding from 1 review

Antibiotic eardrops (with or without a corticosteroid) vs oral antibiotics

Resolution of ear discharge at short‐term

Antibiotic eardrops (with or without a corticosteroid) probably leads to higher resolution of ear discharge at short‐term compared with oral antibiotics (moderate certainty).

1 finding from 1 review

Protease‐modulating matrix dressing regimen vs any other dressing regimen

Proportion of participants with healed ulcers at 6 weeks · people with venous leg ulcers

It is very uncertain whether protease‐modulating matrix dressing regimen changes proportion of participants healed ‐ short term (4‐8 weeks) compared with any other dressing regimen (very low certainty).

1 finding from 1 review

Fractional laser vs radiofrequency

Participant‐assessed adverse events (short‐term) · people with acne scars

The review found no eligible studies for this question.

1 finding from 1 review