Cochrane · systematic review · CD011390

Laparoscopic versus open transhiatal oesophagectomy for oesophageal cancer

Gurusamy, KS, Pallari, E, Midya, S, et al. · Cochrane Database of Systematic Reviews · 2016 · Cochrane Library

GutAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
12
current version
GRADE rated
12
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 12 · 100%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Laparoscopic versus open transhiatal oesophagectomy for oesophageal cancer: primary outcomes

Population: patients with oesophageal cancer
4 questions
OutcomeEffectEvidenceStatus / GRADE
Short‐term mortality (in hospital or within 3 months)
Laparoscopic vs open transhiatal oesophagectomy
RR 0.44 [0.05, 4.09]5 studies · 326 participantsVery low
Downgraded: risk of bias, imprecision
Long‐term mortality
Laparoscopic vs open transhiatal oesophagectomy
HR 0.97 [0.81, 1.16]2 studies · 193 participantsVery low
Downgraded: risk of bias, imprecision
Serious adverse events (proportion)
Laparoscopic vs open transhiatal oesophagectomy
RR 0.49 [0.24, 0.99]3 studies · 213 participantsVery low
Downgraded: risk of bias, imprecision
Anastomotic stenosis
Laparoscopic vs open transhiatal oesophagectomy
RR 1.37 [0.33, 5.7]1 study · 73 participantsVery low
Downgraded: risk of bias, imprecision

Laparoscopic versus open transhiatal oesophagectomy for oesophageal cancer: secondary outcomes

Population: patients with oesophageal cancer
8 questions
OutcomeEffectEvidenceStatus / GRADE
Short‐term recurrence (within 6 months)
Laparoscopic vs open transhiatal oesophagectomy
RR 0.88 [0.04, 18.47]1 study · 20 participantsVery low
Downgraded: risk of bias, imprecision
Long‐term recurrence
Laparoscopic vs open transhiatal oesophagectomy
HR 1 [0.84, 1.18]2 studies · 173 participantsVery low
Downgraded: risk of bias, imprecision
Adverse events (proportion)
Laparoscopic vs open transhiatal oesophagectomy
RR 0.64 [0.48, 0.86]3 studies · 213 participantsVery low
Downgraded: risk of bias, imprecision
Blood transfusion (proportion)
Laparoscopic vs open transhiatal oesophagectomy
RR 0.08 [0, 1.35]1 study · 73 participantsVery low
Downgraded: risk of bias, imprecision
Blood transfusion (quantity)
Laparoscopic vs open transhiatal oesophagectomy
no estimate extracted1 study · 93 participantsVery low
Downgraded: risk of bias, imprecision
Length of hospital stay
Laparoscopic vs open transhiatal oesophagectomy
no estimate extracted3 studies · 266 participantsVery low
Downgraded: risk of bias, imprecision
Positive resection margins
Laparoscopic vs open transhiatal oesophagectomy
RR 0.65 [0.37, 1.12]3 studies · 213 participantsVery low
Downgraded: risk of bias, imprecision
Number of harvested lymph nodes
Laparoscopic vs open transhiatal oesophagectomy
no estimate extracted5 studies · 326 participantsVery low
Downgraded: risk of bias, imprecision