Cochrane · systematic review · CD011391
Laparoscopic versus open distal pancreatectomy for pancreatic cancer
Riviere, D, Gurusamy, KS, Kooby, DA, et al. · Cochrane Database of Systematic Reviews · 2016 · Cochrane Library
GutAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
8
current version
GRADE rated
8
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 8 · 100%Low 0 · 0%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Laparoscopic distal pancreatectomy compared with open distal pancreatectomy for pancreatic cancer
Population: patients with pancreatic cancer
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Short‐term mortality Laparoscopic distal pancreatectomy vs open distal pancreatectomy | OR 0.48 [0.11, 2.17] | 9 studies · 1451 participants | Very low Downgraded: risk of bias |
Long‐term mortality Laparoscopic distal pancreatectomy vs open distal pancreatectomy | HR 0.96 [0.82, 1.12] | 3 studies · 277 participants | Very low Downgraded: risk of bias, imprecision |
Serious adverse events (proportion) Laparoscopic distal pancreatectomy vs open distal pancreatectomy | OR 1.79 [0.53, 6.06] | 3 studies · 206 participants | Very low Downgraded: risk of bias, imprecision |
Pancreatic fistula (grade B or C) Laparoscopic distal pancreatectomy vs open distal pancreatectomy | OR 1.19 [0.47, 3.02] | 4 studies · 246 participants | Very low Downgraded: risk of bias, imprecision |
Laparoscopic distal pancreatectomy compared with open distal pancreatectomy for pancreatic cancer
Population: patients with pancreatic cancer
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Recurrence at maximal Laparoscopic distal pancreatectomy vs open distal pancreatectomy | OR 0.58 [0.32, 1.05] | 2 studies · 184 participants | Very low Downgraded: risk of bias, imprecision |
Adverse events (proportion) Laparoscopic distal pancreatectomy vs open distal pancreatectomy | OR 0.95 [0.54, 1.66] | 4 studies · 246 participants | Very low Downgraded: risk of bias, imprecision |
Length of hospital stay Laparoscopic distal pancreatectomy vs open distal pancreatectomy | no estimate extracted | 5 studies · 1068 participants | Very low Downgraded: risk of bias |
Positive resection margins Laparoscopic distal pancreatectomy vs open distal pancreatectomy | OR 0.74 [0.49, 1.1] | 10 studies · 1466 participants | Very low Downgraded: risk of bias |