Cochrane · systematic review · CD011389
Laparoscopic versus open gastrectomy for gastric cancer
Best, LMJ, Mughal, M, Gurusamy, KS · Cochrane Database of Systematic Reviews · 2016 · Cochrane Library
GutAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
8
current version
GRADE rated
8
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 7 · 87.5%Low 1 · 12.5%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Laparoscopic gastrectomy compared to open gastrectomy for gastric cancer (primary outcomes)
Population: patients with gastric cancer
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Short‐term mortality Laparoscopic gastrectomy vs open gastrectomy | RR 1.6 [0.5, 5.1] | 11 studies · 2335 participants | Low Downgraded: risk of bias |
Long‐term mortality (maximal Laparoscopic gastrectomy vs open gastrectomy | HR 0.94 [0.7, 1.25] | 3 studies · 195 participants | Very low Downgraded: risk of bias, imprecision |
Proportion with a serious adverse event (< 3 months) Laparoscopic gastrectomy vs open gastrectomy | RR 0.6 [0.27, 1.34] | 8 studies · 432 participants | Very low Downgraded: risk of bias, imprecision |
Laparoscopic gastrectomy compared to open gastrectomy for gastric cancer (secondary outcomes)
Population: patients with gastric cancer
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Long‐term recurrence (maximal Laparoscopic gastrectomy vs open gastrectomy | HR 0.95 [0.7, 1.3] | 4 studies · 162 participants | Very low Downgraded: risk of bias, imprecision |
Proportion with an adverse event (< 3 months) Laparoscopic gastrectomy vs open gastrectomy | RR 0.78 [0.6, 1.01] | 11 studies · 2490 participants | Very low Downgraded: risk of bias |
Quantity of perioperative blood transfused Laparoscopic gastrectomy vs open gastrectomy | no estimate extracted | 2 studies · 143 participants | Very low Downgraded: risk of bias, imprecision |
Length of hospital stay Laparoscopic gastrectomy vs open gastrectomy | no estimate extracted | 6 studies · 319 participants | Very low Downgraded: risk of bias, imprecision, inconsistency |
Number of lymph nodes harvested Laparoscopic gastrectomy vs open gastrectomy | no estimate extracted | 9 studies · 472 participants | Very low Downgraded: risk of bias, inconsistency |