Cochrane · systematic review · CD011522
Pregabalin for decreasing pancreatic pain in chronic pancreatitis
Gurusamy, KS, Lusuku, C, Davidson, BR · Cochrane Database of Systematic Reviews · 2016 · Cochrane Library
GutAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
6
current version
GRADE rated
6
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 0 · 0%Low 2 · 33.3%Moderate 4 · 66.7%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Pregabalin versus placebo for decreasing pancreatic pain in chronic pancreatitis
Population: patients with chronic pancreatitis and pancreatic pain
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Health‐related quality of life (short‐term) EORTC QLQ‐C30 Pregabalin vs placebo | no estimate extracted | 1 study · 64 participants | Moderate Downgraded: imprecision |
Serious adverse events Pregabalin vs placebo | RR 1.76 [0.35, 8.96] | 1 study · 64 participants | Low Downgraded: imprecision |
Opiate analgesic requirement (short‐term) Pregabalin vs placebo | no estimate extracted | 1 study · 64 participants | Moderate Downgraded: imprecision |
Adverse events Pregabalin vs placebo | RR 1.71 [1.2, 2.43] | 1 study · 64 participants | Moderate Downgraded: imprecision |
Pain scores (short‐term) Pregabalin vs placebo | no estimate extracted | 1 study · 64 participants | Moderate Downgraded: imprecision |
Hospital admissions Pregabalin vs placebo | RR 0.44 [0.04, 4.62] | 1 study · 64 participants | Low Downgraded: imprecision |