Cochrane · systematic review · CD011521
Duodenum‐preserving pancreatic resection versus pancreaticoduodenectomy for chronic pancreatitis
Gurusamy, KS, Lusuku, C, Halkias, C, et al. · Cochrane Database of Systematic Reviews · 2016 · Cochrane Library
GutAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
11
current version
GRADE rated
10
No studies
1
Included studies
NR
No studies 1 · 9.1%Ungraded 0 · 0%Very low 7 · 63.6%Low 3 · 27.3%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Duodenum‐preserving pancreatic resection versus pancreaticoduodenectomy for chronic pancreatitis (primary outcomes)
Population: people requiring surgery for chronic pancreatitis
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Short‐term mortality Duodenum‐preserving pancreatic resection vs pancreaticoduodenectomy | RR 2.89 [0.31, 26.87] | 5 studies · 269 participants | Very low Downgraded: risk of bias |
Long‐term mortality Duodenum‐preserving pancreatic resection vs pancreaticoduodenectomy | HR 0.65 [0.31, 1.34] | 4 studies · 229 participants | Very low Downgraded: risk of bias |
Serious adverse events Duodenum‐preserving pancreatic resection vs pancreaticoduodenectomy | no estimate extracted | NR | No studies |
Quality of life (3 months to 5 years) Duodenum‐preserving pancreatic resection vs pancreaticoduodenectomy | no estimate extracted | 4 studies · 146 participants | Very low Downgraded: risk of bias |
Quality of life (> 5 years) Duodenum‐preserving pancreatic resection vs pancreaticoduodenectomy | no estimate extracted | 2 studies · 101 participants | Low Downgraded: risk of bias |
Duodenum‐preserving pancreatic resection versus pancreaticoduodenectomy for chronic pancreatitis (secondary outcomes)
Population: people requiring surgery for chronic pancreatitis
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Adverse events (proportion) Duodenum‐preserving pancreatic resection vs pancreaticoduodenectomy | RR 0.55 [0.22, 1.35] | 4 studies · 226 participants | Very low Downgraded: risk of bias |
Adverse events (number of adverse events) Duodenum‐preserving pancreatic resection vs pancreaticoduodenectomy | Rate ratio 0.95 [0.43, 2.12] | 1 study · 43 participants | Very low Downgraded: risk of bias |
Length of hospital stay Duodenum‐preserving pancreatic resection vs pancreaticoduodenectomy | no estimate extracted | 4 studies · 208 participants | Low Downgraded: risk of bias |
Employed Duodenum‐preserving pancreatic resection vs pancreaticoduodenectomy | RR 1.54 [1, 2.37] | 4 studies · 189 participants | Low Downgraded: risk of bias |
New‐onset diabetes Duodenum‐preserving pancreatic resection vs pancreaticoduodenectomy | RR 0.78 [0.5, 1.22] | 5 studies · 269 participants | Very low Downgraded: risk of bias |
Pancreatic exocrine insufficiency Duodenum‐preserving pancreatic resection vs pancreaticoduodenectomy | RR 0.83 [0.68, 1.02] | 4 studies · 189 participants | Very low Downgraded: risk of bias |