Spontaneous space closure · Children and adolescents after extraction of a mandibular permanent first molar (before eruption of the second molar)
In the mandible, distal inclination of the second molar vs upright was not significantly associated with space closure (OR 1.18; not GRADE-rated).
1 finding from 1 review
Early childhood caries (ECC) · Children aged 6 years or younger (preschool children)
Serum 25(OH)D <50 nmol/l (vs ≥75 nmol/l) was associated with higher odds of ECC (OR 2.00; ungraded).
1 finding from 1 review
Intervention not reported
Dental caries (early childhood caries)
The intervention led to lower dental caries (early childhood caries); GRADE not reported.
1 finding from 1 review
Dental caries · Children (<18 years) with vs without dental caries
FokI(rs2228570) recessive model: AA vs AG+GG was not significantly associated with dental caries (OR 1.09); ungraded.
1 finding from 1 review
Negative predictive value for dental caries diagnosis · Children and adults with primary or permanent dentition
Negative predictive values were reported in 10 of the 13 studies that reported sensitivity and specificity; no meta-analysis or GRADE rating was reported.
1 finding from 1 review
no estimate extracted
10 studies
GRADE not reported
Alveolar bone loss · Adults in case-control studies (oral cancer patients vs healthy controls)
Alveolar bone loss did not differ significantly between oral cancer patients and controls (SMD 0.18, 95% CI -2.34 to 2.69; extreme heterogeneity); ungraded.
1 finding from 1 review
Dental caries prevalence · Brazilian children/adolescents in permanent dentition (BMI classified by WHO 2007 Z-score)
Overweight/obesity may make little or no difference to the odds of caries in the permanent dentition (low certainty).
1 finding from 1 review
OR 0.93 [0.78, 1.12]
2 studies
Low
Dental caries: prevalence of root caries · adults
Periodontitis was associated with higher root caries odds (OR 2.10).
1 finding from 1 review
Intervention not reported
Dental caries (early childhood caries)
1 finding from 1 review
AOR 6.5
1 study
GRADE not reported
Dental caries · Children aged 2 to 8 years
The review reported an OR of 1.32 when prenatal vitamin D was measured at 6 to 38 gestational weeks.
2 findings from 1 review
Overall success (composite of clinical and radiographic success) · Human permanent teeth with symptomatic irreversible pulpitis due to carious pulp exposure
Full pulpotomy showed a non-significant trend toward higher success than partial pulpotomy in mature teeth with irreversible pulpitis (ungraded).
1 finding from 1 review
OR 2.16 [0.92, 5.07]
3 studies
GRADE not reported
Midline deviation of the mandibular arch · Children and adolescents after extraction of a mandibular permanent first molar (before eruption of the second molar)
One study found midline deviation more likely after unilateral than bilateral extraction (OR 11.6; single study; not GRADE-rated).
1 finding from 1 review
Gingival index (GI) · Children and/or adolescents (<18 years) without background systemic disease
Probiotics probably make little to no difference to the gingival index versus control (MD 0.04, 95%CI -0.18 to 0.27; low certainty).
1 finding from 1 review
Association between patient age and number of ICLs · Patients (permanent dentition) during or after fixed orthodontic treatment with fixed (multibracket) appliances
Patient age was not significantly associated with the number of ICLs (ungraded).
1 finding from 1 review
Dental caries · Primary school children in Ethiopia
Absence of toothpaste use was not significantly associated with dental caries (OR 1.42, 95% CI -1.278 to 4.109, p=0.3029; ungraded).
1 finding from 1 review
OR 1.42 [-1.278, 4.109]
Studies not reported
GRADE not reported
Reduction in previous year's academic score · Primary school children in Ethiopia
Dental caries was associated with higher odds of a reduction in the previous year's academic score (OR 5.51, 95% CI 1.952-9.066; ungraded).
1 finding from 1 review
OR 5.51 [1.952, 9.066]
Studies not reported
GRADE not reported
Spontaneous space closure · Children and adolescents after extraction of a mandibular permanent first molar (before eruption of the second molar)
In the mandible, Demirjian stage F-G vs D-E was not significantly associated with space closure (OR 0.68; not GRADE-rated).
1 finding from 1 review
Intervention not reported
Overall success (composite of clinical and radiographic success)
1 finding from 1 review
Dental caries · Children (<18 years) with vs without dental caries
In the Real-time quantitative PCR genotyping subgroup, TaqI(rs731236) over-dominant model: TT+CC vs TC showed a significant association with caries (OR 1.52); ungraded.
8 findings from 1 review
Association of vitamin D receptor gene polymorphisms with caries risk in children: a systematic review and… 2024 All outcomesOver-dominant model (TT+CC vs TC) · Children under 18 years; case-control and cross-sectional studies (China, Czech Republic, Turkey, Brazil, India) · Real-time quantitative PCR genotyping
OR 1.52 [1.10, 2.10]
Studies not reported
GRADE not reported
Association of vitamin D receptor gene polymorphisms with caries risk in children: a systematic review and… 2024 All outcomesOver-dominant model (TT+CC vs TC) · Children under 18 years; case-control and cross-sectional studies (China, Czech Republic, Turkey, Brazil, India) · Primary dentition
OR 1.49 [0.97, 2.28]
Studies not reported
GRADE not reported
Association of vitamin D receptor gene polymorphisms with caries risk in children: a systematic review and… 2024 All outcomesOver-dominant model (TT+CC vs TC) · Children under 18 years; case-control and cross-sectional studies (China, Czech Republic, Turkey, Brazil, India) · Asian ethnicity
OR 1.38 [1.02, 1.87]
Studies not reported
GRADE not reported
Show 5 more findings
Enamel surface / cross-sectional microhardness · Human / bovine enamel specimens under cariogenic challenge (in situ / ex vivo)
CO2 laser irradiation changes enamel microhardness versus untreated enamel (MD 49.55, CI 37.74 to 61.37; ungraded, 3 ex-vivo studies, I2=48%); the forest plot shows higher microhardness in laser-treated enamel, although the review text states the opposite.
1 finding from 1 review