Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,281 questions · 1,307 findings · 212 reviews

No studies found 256 · 19.6%GRADE not reported 125 · 9.6%Very low 266 · 20.4%Low 403 · 30.8%Moderate 208 · 15.9%High 49 · 3.7%

Technology‐mediated psychoeducation + standard care intervention vs usual care

Compliance/satisfaction: medication ‐ not compliant ‐ long‐term · schizophrenia

It is very uncertain whether technology‐mediated psychoeducation + standard care intervention changes compliance/satisfaction: medication ‐ not compliant ‐ long‐term compared with standard care intervention (very low certainty).

1 finding from 1 review

Intervention not reported

Percentage of well days during the grass pollen season Well days were those days with a symptom score of less than or equal to 2, and no use of rescue medication Scale from: 0 to 100 · patients with allergic rhinitis1
1 finding from 1 review

Intervention not reported

Percentage of days requiring rescue medication (i.e. as tablets) during the grass pollen season Self recorded each day4 Scale from: 0 to 100 · patients with allergic rhinitis1
1 finding from 1 review

α‐FLUPENTHIXOL vs PLACEBO or β‐FLUPENTHIXOL

Global state: clinically important change in global state needing additional medication ‐ chlorpromazine · patients with schizophrenia

It is very uncertain whether α‐FLUPENTHIXOL changes global state: clinically important change in global state needing… compared with PLACEBO or β‐FLUPENTHIXOL (very low certainty).

1 finding from 1 review

ANY FORM OF PSYCHOEDUCATION vs usual care

Compliance: Poor compliance with medication · patients with schizophrenia

It is very uncertain whether ANY FORM OF PSYCHOEDUCATION changes compliance: Not compliant with medication compared with STANDARD CARE (very low certainty).

1 finding from 1 review

Intervention not reported

Concomitant medication (Anxiolytic ‐ Lorazepam) · people with schizophrenia or like psychosis

The intervention may leads to lower concomitant medication (Anxiolytic ‐ Lorazepam) (low certainty).

1 finding from 1 review

ZOTEPINE vs REMOXIPRIDE

Adverse effects: 2. Extrapyramidal effects ‐ use of antiparkinson medication · patients with schizophrenia

ZOTEPINE showed no clear difference in adverse effects: Extrapyramidal effects ‐ use of antiparkinson… compared with REMOXIPRIDE (low certainty).

1 finding from 1 review

ZOTEPINE vs CLOZAPINE

Adverse effects: 2. Extrapyramidal effects ‐ use of antiparkinson medication · patients with schizophrenia

It is very uncertain whether ZOTEPINE changes adverse effects: Extrapyramidal effects ‐ use of antiparkinson… compared with CLOZAPINE (very low certainty).

1 finding from 1 review

ZOTEPINE vs RISPERIDONE

Adverse effects: Extrapyramidal effects ‐ use of antiparkinson medication ‐ vs 4mg risperidone · patients with schizophrenia

It is very uncertain whether ZOTEPINE changes adverse effects: Extrapyramidal effects ‐ use of antiparkinson… compared with RISPERIDONE (very low certainty).

1 finding from 1 review

ZOTEPINE vs RISPERIDONE

Adverse effects: Extrapyramidal effects ‐ use of antiparkinson medication ‐ vs 8mg risperidone · patients with schizophrenia

It is very uncertain whether ZOTEPINE changes adverse effects: Extrapyramidal effects ‐ use of antiparkinson… compared with RISPERIDONE (very low certainty).

1 finding from 1 review

Summary of findings table ‐ Topical capsaicin vs placebo

Maximum pain while on medication (VAS) · Adult patients aged >=18 years, clinically or radiographically diagnosed with TMD (McNeill 1997 criteria); moderate to severe pain of…

Topical capsaicin (0.025% cream) showed no clear difference in maximum pain while on medication (VAS) compared with placebo; GRADE not reported.

1 finding from 1 review

Resorbable (bioresorbable) plates or screws for fixation vs Titanium plates or screws for fixation

Analgesic medication used (type, dose, frequency) · Adults over 18 years of age with fractures of the facial skeleton including the mandible, maxilla, zygoma (malar); studies on fractures of…

The review found no eligible studies for this question.

1 finding from 1 review
  • Resorbable versus titanium plates for facial fractures 2009 · Cochrane All outcomes
    Up to 3 years postoperatively
    Planned primary outcome not assessed: none of the retrieved studies met the inclusion criteria, so no data were available for analysis. Verbatim (Effects of interventions): "Although 53 studies were retrieved in our…
    0 studies
    No studies found