Cochrane · systematic review · CD009238
Helminth therapy (worms) for allergic rhinitis
Croft, AM, Bager, P, Garg, SK · Cochrane Database of Systematic Reviews · 2012 · Cochrane Library
ENTAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
7
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 6 · 85.7%High 1 · 14.3%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Helminths (worms) for allergic rhinitis
Population: patients with allergic rhinitis1
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
All‐cause study withdrawal Investigator‐recorded | RR 0.75 [0.18, 3.21] | 2 studies · 130 participants | High |
Change in allergic rhinitis daily symptom score during the grass pollen season Each daily symptom score was the summation of (i) runny nose score, (ii) itchy nose score and (iii) sneezing score (each of these scores self recorded on a severity sca... | no estimate extracted | 1 study · 100 participants | Moderate Downgraded: imprecision |
Percentage of well days during the grass pollen season Well days were those days with a symptom score of less than or equal to 2, and no use of rescue medication Scale from: 0 to 100 | no estimate extracted | 1 study · 100 participants | Moderate Downgraded: imprecision |
Total quality of life score over 12 weeks Assessed as the total score over the entire 12‐week study period in the Juniper RQLQ, i.e. a patient‐specific test instrument derived from 28 questions drawn from 7 dimensions (sleep, non‐hay fever symptom... | no estimate extracted | 1 study · 30 participants | Moderate Downgraded: imprecision |
Percentage of days requiring rescue medication (i.e. as tablets) during the grass pollen season Self recorded each day4 Scale from: 0 to 100 | no estimate extracted | 1 study · 100 participants | Moderate Downgraded: imprecision |
Hospitalisation due to any adverse event Investigator‐assessed | RR 2.88 [0.31, 26.69] | 1 study · 96 participants | Moderate Downgraded: imprecision |
Any gastrointestinal adverse event Self recorded | RR 1.79 [1.31, 2.45] | 1 study · 96 participants | Moderate Downgraded: imprecision |