Cochrane · systematic review · CD009777
Flupenthixol versus placebo for schizophrenia
Shen, X, Xia, J, Adams, CE · Cochrane Database of Systematic Reviews · 2012 · Cochrane Library
SchizophreniaAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
2
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 5 · 71.4%Very low 2 · 28.6%Low 0 · 0%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
α‐FLUPENTHIXOL versus PLACEBO or β‐FLUPENTHIXOL for schizophrenia
Population: patients with schizophrenia
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Global state: clinically important change in global state needing additional medication ‐ chlorpromazine α‐FLUPENTHIXOL vs PLACEBO or β‐FLUPENTHIXOL | OR 0.19 [0.05, 0.71] | 1 study · 45 participants | Very low Downgraded: imprecision, indirectness, publication bias |
Mental state and behaviour: clinically important change in general mental state and behaviour α‐FLUPENTHIXOL vs PLACEBO or β‐FLUPENTHIXOL | no estimate extracted | 1 study · 45 participants | Ungraded |
Adverse effects/events: incidence of adverse effects/events α‐FLUPENTHIXOL vs PLACEBO or β‐FLUPENTHIXOL | no estimate extracted | 0 studies · 0 participants | Ungraded |
Service outcomes: hospital admission α‐FLUPENTHIXOL vs PLACEBO or β‐FLUPENTHIXOL | no estimate extracted | 0 studies · 0 participants | Ungraded |
General functioning: Poor social functioning ‐ modified Cooper's ratings5,6 α‐FLUPENTHIXOL vs PLACEBO or β‐FLUPENTHIXOL | RR 1.33 [0.91, 1.96] | 1 study · 45 participants | Very low Downgraded: imprecision, indirectness, publication bias |
Satisfaction with treatment: satisfaction with care for recipients of care or careers α‐FLUPENTHIXOL vs PLACEBO or β‐FLUPENTHIXOL | no estimate extracted | 0 studies · 0 participants | Ungraded |
Economic outcomes: direct costs α‐FLUPENTHIXOL vs PLACEBO or β‐FLUPENTHIXOL | no estimate extracted | 0 studies · 0 participants | Ungraded |