Cochrane · systematic review · CD008381
Psychological and pharmacological interventions for depression in patients with diabetes mellitus and depression
Baumeister, H, Hutter, N, Bengel, J · Cochrane Database of Systematic Reviews · 2012 · Cochrane Library
Metabolic and Endocrine DisordersAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
14
current version
GRADE rated
9
No studies
5
Included studies
NR
No studies 5 · 35.7%Ungraded 0 · 0%Very low 0 · 0%Low 7 · 50%Moderate 2 · 14.3%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Psychological interventions for depression in patients with diabetes mellitus
Population: adults with diabetes mellitus and depression
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Depression remission | OR 2.88 [1.58, 5.25] | 4 studies · 647 participants | Moderate Downgraded: inconsistency |
Diabetes complications | no estimate extracted | NR | No studies |
Death from any cause | no estimate extracted | NR | No studies |
Health‐related quality of life | no estimate extracted | 4 studies · 784 participants | Low Downgraded: imprecision, inconsistency |
Medication adherence/adverse effects | no estimate extracted | 1 study · 291 participants | Low Downgraded: imprecision, inconsistency |
Glycaemic control (HbA1c) [%] | no estimate extracted | 4 studies · 441 participants | Low Downgraded: imprecision, inconsistency |
Healthcare costs [annual costs and effects] | no estimate extracted | 1 study · 208 participants | Low Downgraded: imprecision, inconsistency |
Pharmacological interventions for depression in patients with diabetes mellitus
Population: adults with diabetes mellitus and depression
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Depression remission | OR 2.5 [1.21, 5.15] | 3 studies · 136 participants | Low Downgraded: imprecision |
Diabetes complications | no estimate extracted | NR | No studies |
Death from any cause | no estimate extracted | NR | No studies |
Health‐related quality of life | no estimate extracted | 3 studies · 153 participants | Low Downgraded: risk of bias, imprecision |
Medication adherence/adverse effects | no estimate extracted | 1 study · 28 participants | Low Downgraded: risk of bias, imprecision |
Metabolic control (HbA1c) [%] | no estimate extracted | 5 studies · 238 participants | Moderate Downgraded: risk of bias, imprecision |
Healthcare costs | no estimate extracted | NR | No studies |