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Evidence found and GRADE certainty

76 questions · 82 findings · 30 reviews

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No studies found 3 · 3.7%GRADE not reported 8 · 9.8%Very low 8 · 9.8%Low 31 · 37.8%Moderate 22 · 26.8%High 10 · 12.2%

Periodontal treatment (scaling and root planing, alone or with antimicrobials) vs Alternative (less intensive) periodontal treatment, alone or with placebo

Gestational age (preterm birth < 37 weeks) · Pregnant women considered to have periodontal disease (gingivitis or periodontitis) after dental examination

It is very uncertain whether periodontal treatment (scaling and root planing, alone or with… changes gestational age (preterm birth < 37 weeks) compared with alternative (less intensive) periodontal treatment, alone or with… (very low certainty).

3 findings from 1 review

Planned early birth vs expectant management

Admission to neonatal intensive care unit · preterm prelabour rupture of membranes (PPROM)

Planned early birth probably leads to higher admission to neonatal intensive care compared with expectant management (moderate certainty).

1 finding from 1 review

Planned early birth vs expectant management

Length of maternal hospital stay (days) · preterm prelabour rupture of membranes (PPROM)

Planned early birth showed no clear difference in length of hospital stay (maternal) compared with expectant management (moderate certainty).

1 finding from 1 review

Intervention not reported

Preterm birth (before 37 weeks' gestation) · pregnant women considered to be at risk of developing pre‐eclampsia

The intervention leads to lower preterm birth (before 37 weeks' gestation) (high certainty).

1 finding from 1 review

Vitamin D + calcium + other vitamins and minerals vs calcium + other vitamins and minerals (but no vitamin D)

Preterm birth · pregnant women and their infants..

Vitamin D + calcium + other vitamins and minerals showed no clear difference in preterm birth (less than 37 weeks' gestation) compared with calcium + other vitamins and minerals (but no vitamin D) (low certainty).

1 finding from 1 review

Vitamin E vs placebo, no placebo or other supplements

Preterm birth · pregnant women receiving vitamin E supplementation or control, living in areas where there is either inadequate dietary intake of vitamin…

Any vitamin E supplementation showed no clear difference in preterm birth (less than 37 weeks' gestation) compared with placebo, no placebo or other supplements (high certainty).

1 finding from 1 review

Intervention not reported

Preterm birth (< 37 weeks' gestation) · All pregnant women receiving either vitamin C supplementation or control either in areas where there is inadequate dietary intake or where…

The intervention showed no clear difference in preterm birth (< 37 weeks' gestation) (high certainty).

1 finding from 1 review

Group antenatal care vs individual antenatal care (adjusted data)

Gestational age (preterm birth < 37 weeks) · pregnant women accessing prenatal care

Group antenatal care showed no clear difference in preterm birth (gestational age at time of birth less than 37 weeks'… compared with individual antenatal care (adjusted data) (moderate certainty).

1 finding from 1 review