Cochrane · systematic review · CD000179
Pyridoxine (vitamin B6) supplementation during pregnancy or labour for maternal and neonatal outcomes
Salam, RA, Zuberi, NF, Bhutta, ZA · Cochrane Database of Systematic Reviews · 2015 · Cochrane Library
Pregnancy and ChildbirthAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
4
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 3 · 42.9%Very low 0 · 0%Low 4 · 57.1%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Pyridoxine (B6) versus control
Population: pregnant women, either during the prenatal period or during labour.
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Eclampsia ‐ Antenatal oral pyridoxine versus control Pyridoxine (B6) vs control | no estimate extracted | 3 studies · 1242 participants | Ungraded |
Pre‐eclampsia ‐ Antenatal oral pyridoxine versus control Pyridoxine (B6) vs control | RR 1.71 [0.85, 3.45] | 2 studies · 1197 participants | Low Downgraded: imprecision |
Pre‐eclampsia ‐ Antenatal pyridoxine lozenges versus control Pyridoxine (B6) vs control | RR 1.43 [0.64, 3.22] | 1 study · 944 participants | Low Downgraded: imprecision |
Dental decay (increase in decayed, missing or filled teeth) ‐ Antenatal oral pyridoxine versus control Pyridoxine (B6) vs control | RR 0.84 [0.71, 0.98] | 1 study · 371 participants | Low Downgraded: imprecision |
Dental decay (increase in decayed, missing or filled teeth) ‐ Antenatal pyridoxine lozenges versus control Pyridoxine (B6) vs control | RR 0.68 [0.56, 0.83] | 1 study · 342 participants | Low Downgraded: imprecision |
Preterm birth (before 37 completed weeks of gestation) Pyridoxine (B6) vs control | no estimate extracted | 0 participants | Ungraded |
Low birthweight Pyridoxine (B6) vs control | no estimate extracted | 0 participants | Ungraded |