Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,805 questions · 2,912 findings · 307 reviews · Headline outcomes only

No studies found 706 · 24.2%GRADE not reported 133 · 4.6%Very low 786 · 27%Low 696 · 23.9%Moderate 474 · 16.3%High 117 · 4%

Intervention not reported

Withdrawal of methylphenidate due to adverse events of unknown severity Measured by: proportion of participants withdrawn from treatment Average study duration (range): 4.6 months (21 days to 36 months) · children and adolescents aged 18 years and under diagnosed with ADHD
1 finding from 1 review

Intervention not reported

Withdrawal of methylphenidate due to non‐serious adverse events Measured by: proportion of participants withdrawn from treatment Average study duration (range): 5.60 months (0.6 months to 41 months) · children and adolescents aged 18 years and under diagnosed with ADHD
1 finding from 1 review

Intervention not reported

Withdrawal of methylphenidate for unknown reasons Measure by: proportion of participants withdrawn from treatment Average study duration (range): 6.13 months (1 day to 36 months) · children and adolescents aged 18 years and under diagnosed with ADHD
1 finding from 1 review

Intervention not reported

Child death by two years of age · HIV‐positive women during pregnancy and immediate postpartum period

The intervention showed no clear difference in child death by two years of age (low certainty).

1 finding from 1 review

Capnography and standard monitoring vs standard monitoring

Airway interventions adult subgroup analysis (aged ≥ 18 years)h · patients undergoing PSA

Capnography and standard monitoring probably leads to higher airway interventions adult subgroup analysis (aged ≥ 18 years)h compared with standard monitoring (moderate certainty).

1 finding from 1 review

Anterior prolapse repair: native tissue vs absorbable mesh

Repeat surgery for prolapse (stage 2 or greater) at 2 years · women with anterior compartment pelvic organ prolapse

It is very uncertain whether anterior prolapse repair: native tissue changes repeat surgery for prolapse (stage 2 or greater) at 2 years compared with absorbable mesh (very low certainty).

1 finding from 1 review

Non‐exclusive breastfeeding (foods) vs exclusive breastfeeding

“Food allergy” to 1 or more foods between 1 to 3 years of age · healthy breastfeeding full‐term infants

Non‐exclusive breastfeeding (foods) showed no clear difference in “Food allergy” to 1 or more foods between 1 to 3 years of age compared with exclusive breastfeeding (moderate certainty).

1 finding from 1 review

Foods fortified with zinc plus other micronutrients vs foods fortified with other micronutrients without zinc

Zinc deficiency (as defined by authors, depending on age and gender) · general population of all age groups (including pregnant women) from any country, over two years of age

It is very uncertain whether foods fortified with zinc plus other micronutrients changes zinc deficiency (as defined by authors, depending on age and gender) compared with foods fortified with other micronutrients without zinc (very low certainty).

1 finding from 1 review

Intervention not reported

Death or neurodevelopmental delay at age 2 years · women with term breech delivery

The intervention showed no clear difference in death or neurodevelopmental delay at age 2 years (low certainty).

1 finding from 1 review