Cochrane · systematic review · CD010697

Fortification of staple foods with zinc for improving zinc status and other health outcomes in the general population

Shah, D, Sachdev, HS, Gera, T, et al. · Cochrane Database of Systematic Reviews · 2016 · Cochrane Library

Public HealthAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
5
current version
GRADE rated
5
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 1 · 20%Low 4 · 80%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Foods fortified with zinc alone compared to same foods without adding zinc for improving zinc status and other health outcomes in the general population

Population: General population (over 2 years of age, including pregnant and lactating women)
3 questions
OutcomeEffectEvidenceStatus / GRADE
Serum or plasma zinc (in µmol/L)
Foods fortified with zinc alone vs same foods without adding zinc
no estimate extracted3 studies · 158 participantsLow
Downgraded: risk of bias, imprecision
Stunting (author defined)
Foods fortified with zinc alone vs same foods without adding zinc
RR 0.88 [0.36, 2.13]2 studies · 397 participantsLow
Downgraded: risk of bias, imprecision
Underweight (author defined)
Foods fortified with zinc alone vs same foods without adding zinc
RR 3.1 [0.52, 18.38]2 studies · 397 participantsLow
Downgraded: risk of bias, imprecision

Foods fortified with zinc plus other micronutrients compared to foods fortified with other micronutrients without zinc for improving zinc status and other health outcomes in the general population

Population: General population (over 2 years of age, including pregnant and lactating women)
2 questions
OutcomeEffectEvidenceStatus / GRADE
Zinc deficiency (as defined by authors, depending on age and gender)
Foods fortified with zinc plus other micronutrients vs foods fortified with other micronutrients without zinc
RR 0.17 [0.01, 3.94]1 study · 30 participantsVery low
Downgraded: risk of bias, imprecision, indirectness
Serum or plasma zinc (in µmol/L)
Foods fortified with zinc plus other micronutrients vs foods fortified with other micronutrients without zinc
no estimate extracted4 studies · 250 participantsLow
Downgraded: risk of bias, imprecision