Cochrane · systematic review · CD009926

Subsidising artemisinin‐based combination therapy in the private retail sector

Opiyo, N, Yamey, G, Garner, P · Cochrane Database of Systematic Reviews · 2016 · Cochrane Library

SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
9
current version
GRADE rated
8
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 1 · 11.1%Very low 1 · 11.1%Low 0 · 0%Moderate 0 · 0%High 7 · 77.8%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

ACT subsidies combined with supportive interventions versus no subsidies

Population: Patients seeking treatment for suspected uncomplicated malaria
7 questions
OutcomeEffectEvidenceStatus / GRADE
ACT use (percentage of children under 5 years receiving ACT on the same day or following day of fever onset)
ACT subsidies combined with supportive interventions vs no subsidies
no estimate extracted1 study · 26626 participantsHigh
ACT availability (percentage of outlets stocking ACTs for children under 5 years)
ACT subsidies combined with supportive interventions vs no subsidies
no estimate extracted1 study · 2 participantsHigh
ACT availability (percentage of outlets stocking at least one ACT for patients of any age)
ACT subsidies combined with supportive interventions vs no subsidies
no estimate extracted1 study · 1 participantsVery low
Downgraded: risk of bias, indirectness
ACT price (change in ACT prices for children under 5 years)c
ACT subsidies combined with supportive interventions vs no subsidies
no estimate extracted1 study · 1 participantsHigh
ACT market share (volume of ACTs purchased as a proportion of all antimalarials purchased; all age groups)
ACT subsidies combined with supportive interventions vs no subsidies
no estimate extracted1 study · 2 participantsHigh
Use of older antimalarials (amodiaquine, sulphadoxine‐pyrimethamine; children under 5 years)
ACT subsidies combined with supportive interventions vs no subsidies
no estimate extracted1 study · 1 participantsHigh
Adverse effects (such as the number of people receiving ACTs who do not have malaria)
ACT subsidies combined with supportive interventions vs no subsidies
no estimate extracted3 studies · 3 participantsUngraded

ACT price vouchers versus no subsidies

Population: Patients seeking treatment for suspected uncomplicated malaria
2 questions
OutcomeEffectEvidenceStatus / GRADE
ACT access (percentage of illness episodes treated with ACTs; all age groups)
ACT price vouchers vs no subsidies
no estimate extracted1 study · 2789 participantsHigh
ACT targeting (percentage of ACT takers who are malaria positive; all age groups)
ACT price vouchers vs no subsidies
no estimate extracted1 study · 2789 participantsHigh