Cochrane · systematic review · CD003669
Regional (spinal, epidural, caudal) versus general anaesthesia in preterm infants undergoing inguinal herniorrhaphy in early infancy
Jones, LJ, Craven, PD, Lakkundi, A, et al. · Cochrane Database of Systematic Reviews · 2015 · Cochrane Library
NeonatalAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
6
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 1 · 14.3%Very low 0 · 0%Low 3 · 42.9%Moderate 3 · 42.9%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Regional (spinal, epidural, caudal) versus general anaesthesia for preterm infants having inguinal herniorrhaphy in early infancy
Population: Preterm infants requiring surgery for inguinal hernia in early infancy
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Neurodevelopmental status at 2 years corrected age Regional (spinal, epidural, caudal) vs general anaesthesia | no estimate extracted | 0 studies · 0 participants | Ungraded |
Apnoea/bradycardia occurring 12‐24 hours following completion of operation Regional (spinal, epidural, caudal) vs general anaesthesia | RR 0.72 [0.48, 1.06] | 4 studies · 138 participants | Moderate Downgraded: risk of bias |
Any oxygen desaturation occurring 12‐24 hours following completion of the operation Regional (spinal, epidural, caudal) vs general anaesthesia | RR 0.82 [0.61, 1.11] | 2 studies · 48 participants | Moderate Downgraded: risk of bias |
Use of post‐operative respiratory support Regional (spinal, epidural, caudal) vs general anaesthesia | RR 0.09 [0.01, 1.64] | 3 studies · 98 participants | Low Downgraded: risk of bias, imprecision |
Post‐operative apnoea with preoperative sedatives excluded Regional (spinal, epidural, caudal) vs general anaesthesia | RR 0.53 [0.34, 0.82] | 4 studies · 129 participants | Moderate Downgraded: risk of bias |
Anaesthetic agent failure Regional (spinal, epidural, caudal) vs general anaesthesia | RR 7.83 [1.51, 40.58] | 3 studies · 92 participants | Low Downgraded: risk of bias, imprecision |
Anaesthetic placement failure Regional (spinal, epidural, caudal) vs general anaesthesia | RR 7.38 [0.98, 55.52] | 3 studies · 90 participants | Low Downgraded: risk of bias, imprecision |