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What do systematic reviews say?

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Evidence found and GRADE certainty

690 questions · 711 findings · 93 reviews

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No studies found 167 · 23.5%GRADE not reported 36 · 5.1%Very low 181 · 25.5%Low 202 · 28.4%Moderate 100 · 14.1%High 25 · 3.5%

Summary of findings: 1.25 mg/day plus rehabilitation vs placebo plus rehabilitation

Symptom free with activities of daily living (patient rated) ( · rotator cuff disease

Summary of findings: 1.25 mg/day plus rehabilitation showed no clear difference in symptom free with activities of daily living (patient rated) ( compared with placebo plus rehabilitation (low certainty).

1 finding from 1 review

Summary of findings: plantar‐incision neurectomy (PN) vs dorsal‐incision neurectomy (DN)

Satisfaction: 4‐item Likert scale (dichotomised into satisfied and dissatisfied) · Morton's neuroma

Summary of findings: plantar‐incision neurectomy (PN) showed no clear difference in satisfaction: 4‐item Likert scale (dichotomised into satisfied and… compared with dorsal‐incision neurectomy (DN) (low certainty).

1 finding from 1 review

Summary of findings table ‐ Purse‐string skin closure vs linear skin closure

Participant satisfaction (very satisfied or satisfied) · people undergoing stoma reversal

Summary of findings table ‐ Purse‐string skin closure may leads to higher participant satisfaction (very satisfied or satisfied) compared with linear skin closure (low certainty).

1 finding from 1 review

Summary of findings: split‐spinous process laminotomy vs conventional laminectomy

Satisfactory recovery Bilateral laminotomy compared with conventional laminectomy Satisfactory recovery was defined as 'good' or 'excellent' self‐perceived recovery · patients with lumbar stenosis

Summary of findings: split‐spinous process laminotomy led to lower satisfactory recovery Split‐spinous process laminotomy compared with… compared with conventional laminectomy; GRADE not reported.

1 finding from 1 review

Summary of findings table ‐ Stem Cell vs placebo or control

CDAI <150 at 24 weeks · Induction of Remission in Medically Refractory Crohn's Disease

It is very uncertain whether summary of findings table ‐ Stem Cell changes CDAI <150 at 24 weeks compared with placebo or Control (very low certainty).

1 finding from 1 review

Summary of findings table ‐ Stem Cell vs placebo or control

Fistula Closure short‐term · Induction of Remission in Medically Refractory Crohn's Disease

Summary of findings table ‐ Stem Cell may leads to higher fistula Closure short‐term compared with placebo or Control (low certainty).

1 finding from 1 review

Summary of findings table ‐ Stem Cell vs placebo or control

Fistula closure in long‐term · Induction of Remission in Medically Refractory Crohn's Disease

Summary of findings table ‐ Stem Cell may leads to higher fistula closure in long‐term compared with placebo or Control (low certainty).

1 finding from 1 review

Summary of findings table ‐ Stem Cell vs placebo or control

Total adverse events · Induction of Remission in Medically Refractory Crohn's Disease

It is very uncertain whether summary of findings table ‐ Stem Cell changes total Adverse Events compared with placebo or Control (very low certainty).

1 finding from 1 review

Summary of findings table ‐ Stem Cell vs placebo or control

Withdrawals due to adverse events · Induction of Remission in Medically Refractory Crohn's Disease

It is very uncertain whether summary of findings table ‐ Stem Cell changes withdrawal due to adverse events compared with placebo or Control (very low certainty).

1 finding from 1 review

Organisational interventions vs usual care

Number of people sustaining one or more fall‐related fractures · older people in all long‐term care settings

Summary of findings table ‐ Organisational intervention showed no clear difference in residents with at least one fall‐related fracture compared with usual care (low certainty).

1 finding from 1 review

Summary of findings: Assessment/screening interventions vs control

Functional ability · stroke survivors with visual field defects

It is very uncertain whether summary of findings: Assessment/screening interventions changes functional ability in activities of daily living (FIM) After… compared with control (very low certainty).

1 finding from 1 review