Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

690 questions · 711 findings · 93 reviews

No studies found 167 · 23.5%GRADE not reported 36 · 5.1%Very low 181 · 25.5%Low 202 · 28.4%Moderate 100 · 14.1%High 25 · 3.5%

Summary of findings: ACT vs CQ

Effective treatment of the blood stage parasite As assessed by: Recurrent parasitaemia before day 28 · Adults and children with uncomplicated P. vivax malaria

Summary of findings: ACT showed no clear difference in effective treatment of the blood stage parasite As assessed by:… compared with CQ (high certainty).

1 finding from 1 review

Summary of findings: ACT vs CQ

Post‐treatment prophylaxis As assessed by: Recurrent parasitaemia between day 28 and day 42/56/63 · Adults and children with uncomplicated P. vivax malaria

Summary of findings: ACT may leads to lower post‐treatment prophylaxis As assessed by: Recurrent parasitaemia… compared with CQ (low certainty).

1 finding from 1 review

Summary of findings: walking programme (general physical activity) vs control (e.g. usual activities)

Number of people sustaining one or more fall‐related fractures · Older people living in the community (trials focusing on people recently discharged from hospital were not included)

It is very uncertain whether summary of findings: walking programme (general physical activity) changes number of people who experienced one or more fall‐related fractures compared with control (e.g. usual activities) (very low certainty).

1 finding from 1 review

Summary of findings. Home vs hospital‐clinic removal of casts

Participant satisfaction: Parents would not choose the same treatment again (6 weeks · children with stable wrist fracture, predominantly buckle (torus) fracturesa

Summary of findings. Home may leads to lower participant satisfaction: Parents would not choose the same… compared with hospital‐clinic removal of casts (low certainty).

1 finding from 1 review

Summary of findings. Bandage vs cast

Participant satisfaction: children found treatment was convenient (4 weeks · children with stable wrist fracture, predominantly buckle (torus) fracturesa

It is very uncertain whether summary of findings. Bandage changes participant satisfaction: children found treatment was convenient (4… compared with cast (very low certainty).

1 finding from 1 review

Multifactorial interventions vs usual care

Risk of fracture Length of · and

It is very uncertain whether summary of findings: Multifactorial interventions changes risk of fracture Length of compared with usual care (very low certainty).

2 findings from 1 review