Cochrane · systematic review · CD014687
Treatments for Morton's neuroma
Matthews, BG, Thomson, CE, Harding, MP, et al. · Cochrane Database of Systematic Reviews · 2024 · Cochrane Library
NeuromuscularAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
15
current version
GRADE rated
11
No studies
4
Included studies
NR
No studies 4 · 26.7%Ungraded 0 · 0%Very low 1 · 6.7%Low 7 · 46.7%Moderate 3 · 20%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Summary of findings: corticosteroid and local anaesthetic injection (CS+LA) versus local anaesthetic injection (LA) for people with Morton's neuroma
Population: Morton's neuroma
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Pain: VAS(0 to 100; a lower score indicates less pain) (change from baseline and final values) Summary of findings: corticosteroid and local anaesthetic injection (CS+LA) vs local anaesthetic injection (LA) | no estimate extracted | 2 studies · 157 participants | Low Downgraded: risk of bias, imprecision |
Function: Summary of findings: corticosteroid and local anaesthetic injection (CS+LA) vs local anaesthetic injection (LA) | no estimate extracted | 2 studies · 157 participants | Low Downgraded: risk of bias, imprecision |
HRQoL: EQ‐5D (0 to 1; a higher score indicates improved HRQoL) (final values) Summary of findings: corticosteroid and local anaesthetic injection (CS+LA) vs local anaesthetic injection (LA) | no estimate extracted | 1 study · 122 participants | Moderate Downgraded: risk of bias, imprecision |
Satisfaction: Modified Johnson Scale (dichotomised into satisfied and dissatisfied) Summary of findings: corticosteroid and local anaesthetic injection (CS+LA) vs local anaesthetic injection (LA) | RR 1.08 [0.63, 1.85] | 1 study · 35 participants | Low Downgraded: risk of bias, imprecision |
Adverse events Summary of findings: corticosteroid and local anaesthetic injection (CS+LA) vs local anaesthetic injection (LA) | RR 9.84 [1.28, 75.56] | 2 studies · 157 participants | Very low Downgraded: risk of bias, imprecision |
Summary of findings: ultrasound‐guided injection of corticosteroid and local anaesthetic (UG CS+LA) versus non‐ultrasound‐guided injection of corticosteroid and local anaesthetic (NUG CS+LA) for people with Morton's neuroma
Population: Morton's neuroma
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Pain: VAS (0 to 100; a lower score indicates less pain) (final values) Summary of findings: ultrasound‐guided injection of corticosteroid and local anaesthetic (UG CS+LA) vs non‐ultrasound‐guided injection of corticosteroid and local anaesthetic (NUG CS+LA) | no estimate extracted | 2 studies · 116 participants | Moderate Downgraded: risk of bias, imprecision |
Function: Summary of findings: ultrasound‐guided injection of corticosteroid and local anaesthetic (UG CS+LA) vs non‐ultrasound‐guided injection of corticosteroid and local anaesthetic (NUG CS+LA) | no estimate extracted | 2 studies · 116 participants | Moderate Downgraded: risk of bias, imprecision |
HRQoL Summary of findings: ultrasound‐guided injection of corticosteroid and local anaesthetic (UG CS+LA) vs non‐ultrasound‐guided injection of corticosteroid and local anaesthetic (NUG CS+LA) | no estimate extracted | NR | No studies |
Satisfaction: 4‐point Likert scale (dichotomised into satisfied and dissatisfied) Summary of findings: ultrasound‐guided injection of corticosteroid and local anaesthetic (UG CS+LA) vs non‐ultrasound‐guided injection of corticosteroid and local anaesthetic (NUG CS+LA) | RR 1.71 [1.19, 2.44] | 2 studies · 114 participants | Low Downgraded: risk of bias, imprecision |
Adverse events Summary of findings: ultrasound‐guided injection of corticosteroid and local anaesthetic (UG CS+LA) vs non‐ultrasound‐guided injection of corticosteroid and local anaesthetic (NUG CS+LA) | RR 0.42 [0.12, 1.39] | 2 studies · 116 participants | Low Downgraded: risk of bias, imprecision |
Summary of findings: plantar‐incision neurectomy (PN) versus dorsal‐incision neurectomy (DN) for people with Morton's neuroma
Population: Morton's neuroma
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Pain: VAS(0 to 100; lower score indicates less pain) Summary of findings: plantar‐incision neurectomy (PN) vs dorsal‐incision neurectomy (DN) | no estimate extracted | NR | No studies |
Function: restrictions in daily activities (4‐item Likert scale) Summary of findings: plantar‐incision neurectomy (PN) vs dorsal‐incision neurectomy (DN) | no estimate extracted | NR | No studies |
HRQoL Summary of findings: plantar‐incision neurectomy (PN) vs dorsal‐incision neurectomy (DN) | no estimate extracted | NR | No studies |
Satisfaction: 4‐item Likert scale (dichotomised into satisfied and dissatisfied) Summary of findings: plantar‐incision neurectomy (PN) vs dorsal‐incision neurectomy (DN) | RR 1.06 [0.87, 1.28] | 1 study · 73 participants | Low Downgraded: risk of bias, imprecision |
Adverse events Summary of findings: plantar‐incision neurectomy (PN) vs dorsal‐incision neurectomy (DN) | RR 0.95 [0.32, 2.85] | 1 study · 75 participants | Low Downgraded: risk of bias, imprecision |