CRP (mg/dL) at end of study · People with periodontitis and metabolic syndrome (no CVD; primary prevention)
1 finding from 1 review
Intervention not reported
Difference in summary specificity (NMA, Analysis 2)
1 finding from 1 review
Intervention not reported
Difference in summary sensitivity (NMA, Analysis 2)
1 finding from 1 review
Caries arrest · Children with dentine carious lesions (ICDAS 4-5) in primary teeth
Twice-yearly 38% SDF was reported to arrest more caries than once-yearly application (24-month rates 91% vs 79%; ungraded).
1 finding from 1 review
Immediate bond strength (MPa) · Dental adhesives bonded to caries-affected dentin (in vitro)
Only one study assessed SDF without a rinsing step on adhesive bonding to caries-affected dentin (Kucukyilmaz 2016, which reported impaired bond strength); no meta-analysis was possible, so no pooled estimate is available.
1 finding from 1 review
Contribution of dental care products to total fluoride exposure · Pregnant and lactating women
No study has explored the contribution of dental care products to total fluoride exposure in pregnant and lactating women.
1 finding from 1 review
no estimate extracted
0 studies
No studies found
Presence of dry socket · Adults (>18 years) having permanent tooth extraction (predominantly mandibular third molars)
Artemisia desertorum spreng (Shahaosan) showed no clear difference in presence of dry socket compared with artemisia desertorum spreng (Yunnan); GRADE not reported.
1 finding from 1 review
MRONJ (incidence proportion) · People with cancer treated with intravenous bisphosphonates undergoing dental extractions (at risk of MRONJ)
It is very uncertain whether dental extraction protocol with plasma rich in growth factors (PRGF)… changes MRONJ (incidence proportion) compared with standard dental extraction protocol without PRGF (very low certainty).
1 finding from 1 review
Postobturation pain at 1 week · People aged 10 years or above requiring root canal treatment; permanent teeth with completely formed apex and without internal resorption
It is very uncertain whether single-visit root canal treatment changes postobturation pain at 1 week compared with multiple-visit root canal treatment (two or more visits) (very low certainty).
1 finding from 1 review
Middle SES prevalence (among children with caries) · Children with dental caries (deciduous and/or permanent dentition) in low- and middle-income countries
About 35% of children with caries in LMICs were of middle SES (pooled prevalence 0.353, 95% CI 0.180 to 0.550; 7 studies; not GRADE-rated).
1 finding from 1 review
Presence of dry socket · Adults (>18 years) having permanent tooth extraction (predominantly mandibular third molars)
Oral tissue patch led to lower presence of dry socket compared with placebo or control; GRADE not reported.
1 finding from 1 review
Oral candidiasis prevalence · Children and adolescents (<18 years) living with HIV (CLWH)
cART was associated with a significantly lower prevalence of oral candidiasis than monotherapy or dual therapy (very low certainty).
1 finding from 1 review
OR 0.22 [0.16, 0.29]
4 studies
Very low
Tooth loss · Adults with a clinical diagnosis of (chronic) periodontitis (1999 classification); studies of aggressive periodontitis, systemic disorders…
The review found no eligible studies for this question.
1 finding from 1 review
High SES prevalence (among children with caries) · Children with dental caries (deciduous and/or permanent dentition) in low- and middle-income countries
About 25% of children with caries in LMICs were of high SES (pooled prevalence 0.245, 95% CI 0.162 to 0.339; 5 studies; not GRADE-rated).
1 finding from 1 review
Food preference · Children and adolescents (general population, aged under 20 years)
In crossover studies with binary outcomes, food marketing increased food preference (OR 3.49, 95% CI 2.03 to 6.22; ungraded).
1 finding from 1 review
OR 3.49 [2.03, 6.22]
4 studies
GRADE not reported
Caries development in permanent teeth · School children and adolescents (6-18 years) followed from primary dentition (baseline examination before 72 months of age)
Early-childhood oral hygiene and dietary habits show inconsistent associations with permanent-teeth caries, often losing significance after adjustment for past caries (2 studies; not pooled; not GRADE-rated).
1 finding from 1 review
Linear gingival erythema (WHO clinical stage 2) · Children or adolescents
No difference in linear gingival erythema between groups (pooled OR 1.00, 95% CI 0.06 to 16.19); the lesion was essentially absent in both groups.
1 finding from 1 review
Dental caries · Healthy, term-born, normal-birth-weight infants aged 4-24 months (breastfed and/or formula-fed) in Western industrialized countries
No eligible studies examined the influence of complementary feeding practices on later dental caries; this is an evidence gap.
1 finding from 1 review
Study-specific disease-state discrimination · Oral microbiome samples in 15 case-controlled studies
Bong-Soo 2017, Zhu 2018, and Jiang 2019 had mean AUC scores over 0.75; exact study-specific AUCs were not reported in text or readable figure labels.
1 finding from 1 review
no estimate extracted
15 studies
GRADE not reported
Molar caries detection accuracy · Dental images of human beings
The review reported 89% accuracy for molar caries in Lee et al. (Ungraded).
1 finding from 1 review