Disability caused by pain at follow-up · People aged 12 years and over with painful TMD lasting 3 months or longer
Cognitive behavioural therapy (CBT) showed no clear difference in pain disability at treatment completion compared with usual care, waiting list or no treatment (control) (low certainty).
2 findings from 1 review
Chronic herpes simplex infection prevalence · Children and adolescents (<18 years) living with HIV (CLWH)
No significant difference in chronic herpes simplex infection between ART regimens (very low certainty).
1 finding from 1 review
Proportion of children with other untreated oral health needs · School children (aged 4 to 15 years), primary and secondary schools in the UK and India
The review found no eligible studies for this question.
1 finding from 1 review
Crown retention · Children with primary (deciduous) teeth requiring full-coverage crown restoration
Zirconia crowns showed no significant difference in crown retention versus other restorations at 6 months (RR 1.02, 95% CI 0.94 to 1.11; 3 studies; not GRADE-rated).
2 findings from 1 review
Intervention not reported
Caries experience - mean dfs (descriptive), primary dentition
1 finding from 1 review
Primary maternal education prevalence (among children with caries) · Children with dental caries (deciduous and/or permanent dentition) in low- and middle-income countries
About 42% of children with caries in LMICs had mothers with primary education (pooled prevalence 0.425, 95% CI 0.280 to 0.576; 7 studies; not GRADE-rated).
1 finding from 1 review
Development of endocarditis due to other (non-dental) causes · Adults or children at increased risk of bacterial endocarditis (pre-existing cardiac condition) undergoing an invasive dental procedure
The review found no eligible studies for this question.
1 finding from 1 review
Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · People aged 12 years and over with painful TMD lasting 3 months or longer
1 finding from 1 review
MRONJ (incidence proportion) · Men with metastatic prostate cancer receiving intravenous zoledronic acid (at risk of MRONJ)
It is very uncertain whether dental examinations at three-month intervals and preventive treatments changes MRONJ (incidence proportion) compared with standard care (very low certainty).
1 finding from 1 review
Caries increment, tooth index D(M)FT · Primary school children (aged 3-16 years) attending primary school in low- and middle-income countries (LMICs)
Among children aged 5-8 years, net increment in DMFT was not significantly reduced (SMD -0.36); no significant subgroup difference by age.
3 findings from 1 review
Intervention not reported
Difference in summary specificity (NMA, Analysis 2)
1 finding from 1 review
Reduction in level of contamination by particles <=5 um (droplet nuclei) at >=2 m from patient's oral cavity · Dental patients undergoing aerosol-generating procedures (AGPs) and the dental healthcare providers treating them
It is very uncertain whether chlorhexidine (CHX) changes reduction in level of contamination by particles <=5 um (droplet… compared with ozonated water (very low certainty).
2 findings from 1 review
Specificity for detection of enamel caries · Asymptomatic children or adults suspected of enamel caries (clinical studies); extracted teeth (in vitro studies)
Radiographic imaging had a summary specificity of 0.89 (95% CrI 0.83, 0.93) for detecting enamel caries; low certainty.
2 findings from 1 review
Treatment failure (annual failure rate) · Children with previously unrestored, vital carious lesions in primary teeth (no pulp therapy); aged 1.5-11 years
Compomer had an annual failure rate of 0-14.7% (7 RCTs), comparable to amalgam/RMGIC/composite and better than high-viscosity GIC; low quality of evidence (ungraded).
1 finding from 1 review
Presence of dry socket · Adults (>18 years) having permanent tooth extraction (predominantly mandibular third molars)
Metronidazole gel (25%, intrasocket) showed no clear difference in presence of dry socket compared with placebo gel; GRADE not reported.
1 finding from 1 review
Overweight/obesity risk · Healthy children aged 6–24 months in Western industrialized countries
NRCF showed no significant association with overweight/obesity across the reported comparisons (very low certainty).
1 finding from 1 review
Restoration failure · Children with carious primary teeth
No comparative effect estimate was reported; both arms had 0% failure.
1 finding from 1 review
Oral hairy leukoplakia (WHO clinical stage 3) · Children or adolescents
No difference in oral hairy leukoplakia between groups (pooled OR 1.00, 95% CI 0.06 to 16.19); lesion essentially absent in both.
1 finding from 1 review
Caries arrest · Children with dentine carious lesions (ICDAS 4-5) in primary teeth
A second meta-analysis reported odds ratios of 2.44 to 3.63 favouring 38% SDF over fluoride varnish/water for caries arrest (ungraded).
2 findings from 1 review
OR (caries arrest) OR 2.44-3.63 (range); 2.44 = Chu estimate including 30% SDF
3 studies
GRADE not reported
Proportion (caries arrest) 81 [68, 89]
12 studies
GRADE not reported
Sensitivity for detection of enamel caries · Asymptomatic children or adults suspected of enamel caries (clinical studies); extracted teeth (in vitro studies)
In the fully within-person analysis, radiographic imaging had a summary sensitivity of 0.48 (95% CrI 0.35, 0.62); ungraded.
2 findings from 1 review