Question · asked by 1 review

Dental examinations at three-month intervals and preventive treatments vs usual care: MRONJ (incidence proportion)

Population
Men with metastatic prostate cancer receiving intravenous zoledronic acid (at risk of MRONJ)
Intervention
Dental examinations at three-month intervals and preventive treatments
Comparison
usual care
Outcome
MRONJ (incidence proportion)

It is very uncertain whether dental examinations at three-month intervals and preventive treatments changes MRONJ (incidence proportion) compared with standard care (very low certainty).

What each review found

Include earlier review versions
FindingEffectStudiesGRADE certainty
Dental examinations at three-month intervals and preventive treatments vs Standard care
MRONJ (incidence proportion) · Men with metastatic prostate cancer receiving intravenous zoledronic acid (at risk of MRONJ) · mean 32 months
It is very uncertain whether dental examinations at three-month intervals and preventive treatments changes MRONJ (incidence proportion) compared with standard care (very low certainty).
Interventions for managing medication‐related osteonecrosis of the jaw (2022) · Cochrane All outcomes
RR 0.10 [0.02, 0.39]1 study · 253 participantsVery low

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Interventions for managing medication‐related osteonecrosis of the jaw
2022 · Cochrane All outcomes
2021-06Not listedNot assessed
How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.