Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

82 questions · 83 findings · 60 reviews

No studies found 4 · 4.8%GRADE not reported 9 · 10.8%Very low 25 · 30.1%Low 26 · 31.3%Moderate 12 · 14.5%High 7 · 8.4%

Fingolimod 0.5 mg vs placebo

Withdrawals due to adverse events · patients with relapsing‐remitting multiple sclerosis

It is very uncertain whether fingolimod 0.5 mg changes withdrawals due to adverse events compared with placebo (very low certainty).

1 finding from 1 review

Oxycodone MR vs placebo

Withdrawals due to adverse events · adults with neuropathic pain (2 studies in peripheral diabetic neuropathy and 1 study in postherpetic neuralgia)
1 finding from 1 review

Chondroitin vs placebo

Withdrawals due to adverse events · patients with osteoarthritis

Chondroitin showed no clear difference in withdrawals due to adverse events compared with placebo (moderate certainty).

1 finding from 1 review

Cromolyn sodium vs placebo

Withdrawals due to adverse events · active EoE pediatric patients

Cromolyn sodium showed no clear difference in withdrawals due to adverse events at 8 weeks compared with placebo (low certainty).

1 finding from 1 review

Viaskin milk patch vs placebo

Withdrawals due to adverse events · active EoE pediatric patients

Viaskin milk patch showed no clear difference in withdrawals due to adverse events at 44 weeks compared with placebo (low certainty).

1 finding from 1 review