Cochrane · systematic review · CD006790
Type I interferons for induction of remission in ulcerative colitis
Wang, Y, MacDonald, JK, Benchimol, EI, et al. · Cochrane Database of Systematic Reviews · 2015 · Cochrane Library
GutAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
4
current version
GRADE rated
4
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 0 · 0%Low 2 · 50%Moderate 2 · 50%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Type I Interferons compared to placebo for induction of remission in ulcerative colitis
Population: patients with induction of remission in ulcerative colitis
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Remission Type I Interferons vs placebo | RR 1.16 [0.84, 1.58] | 4 studies · 362 participants | Moderate Downgraded: imprecision |
Clinical improvement Type I Interferons vs placebo | RR 1.16 [0.96, 1.4] | 4 studies · 425 participants | Moderate Downgraded: imprecision |
Serious adverse events Type I Interferons vs placebo | RR 0.74 [0.13, 4.14] | 4 studies · 468 participants | Low Downgraded: imprecision |
Withdrawals due to adverse events Type I Interferons vs placebo | RR 3.16 [1.06, 9.4] | 4 studies · 394 participants | Low Downgraded: imprecision |