Cochrane · systematic review · CD010692
Oxycodone for neuropathic pain in adults
Gaskell, H, Derry, S, Stannard, C, et al. · Cochrane Database of Systematic Reviews · 2016 · Cochrane Library
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
6
current version
GRADE rated
6
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 6 · 100%Low 0 · 0%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Show all 2 versionsOxycodone MR compared with placebo for neuropathic pain
Population: adults with neuropathic pain (2 studies in peripheral diabetic neuropathy and 1 study in postherpetic neuralgia)
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
'Substantial benefit' (≥ 50% reduction in pain or PGIC very much improved) Oxycodone MR vs placebo | no estimate extracted | NR | Very low |
'Moderate benefit' (≥ 30% reduction in pain or PGIC much or very much improved) Oxycodone MR vs placebo | no estimate extracted | 3 studies · 537 participants | Very low |
Withdrawals due to adverse events Oxycodone MR vs placebo | no estimate extracted | 5 studies · 680 participants | Very low |
Withdrawals due to lack of efficacy Oxycodone MR vs placebo | no estimate extracted | 5 studies · 680 participants | Very low |
Serious adverse events Oxycodone MR vs placebo | no estimate extracted | 4 studies · 352 participants | Very low |
Death Oxycodone MR vs placebo | no estimate extracted | 5 studies · 680 participants | Very low |