Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

139 questions · 139 findings · 39 reviews

No studies found 37 · 26.6%GRADE not reported 0 · 0%Very low 49 · 35.3%Low 37 · 26.6%Moderate 12 · 8.6%High 4 · 2.9%

Intervention not reported

Serious adverse events · people with cancer pain
1 finding from 1 review

Cycled inhaled tobramycin vs culture‐based TNS

Adverse effects of antibiotics: proportion of participants with one or more serious adverse event · adults and children with cystic fibrosis and a positive microbiological isolate of P aeruginosa from a respiratory tract specimen

Cycled inhaled tobramycin (TNS) probably leads to lower adverse effects of antibiotics: proportion of participants with one… compared with culture‐based TNS (moderate certainty).

1 finding from 1 review

Intervention not reported

Serious adverse events (SAEs) ‐ Network included 31 pairwise comparisons ‐ Mean risk with SUN across trials3 included in this network: 40.7% · people with a confirmed diagnosis of advanced renal cell carcinoma (combined risk groups) without previous systemic anticancer therapy

The intervention showed no clear difference in serious adverse events (SAEs) ‐ Network included 31 pairwise… (moderate certainty).

1 finding from 1 review

Tramadol vs paracetamol

Number of participants experiencing any serious adverse events · patients with osteoarthritis

The review found no eligible studies for this question.

1 finding from 1 review