Cochrane · systematic review · CD012508
Tramadol with or without paracetamol (acetaminophen) for cancer pain
Wiffen, PJ, Derry, S, Moore, RA · Cochrane Database of Systematic Reviews · 2017 · Cochrane Library
Pain, Palliative and Supportive CareAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
7
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 7 · 100%Low 0 · 0%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Oral tramadol compared with oral morphine for cancer pain
Population: people with pain due to cancer
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Participants with pain reduction of 30% or greater from baseline Oral tramadol vs oral morphine | no estimate extracted | 1 study · 227 participants | Very low |
Participants with pain reduction of 50% or greater from baseline Oral tramadol vs oral morphine | no estimate extracted | 1 study · 227 participants | Very low |
Participants with pain no worse than mild Oral tramadol vs oral morphine | no estimate extracted | 1 study · 227 participants | Very low |
Participants with PGIC of much improved or very much improved Oral tramadol vs oral morphine | no estimate extracted | 1 study · 227 participants | Very low |
Serious adverse events (death) Oral tramadol vs oral morphine | no estimate extracted | 2 studies · 280 participants | Very low |
Other adverse events Oral tramadol vs oral morphine | no estimate extracted | NR | Very low |
Withdrawals Oral tramadol vs oral morphine | no estimate extracted | NR | Very low |