Cochrane · systematic review · CD012637

Oral paracetamol (acetaminophen) for cancer pain

Wiffen, PJ, Derry, S, Moore, RA, et al. · Cochrane Database of Systematic Reviews · 2017 · Cochrane Library

SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
8
current version
GRADE rated
8
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 8 · 100%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Comparison

Population: people with cancer pain
8 questions
OutcomeEffectEvidenceStatus / GRADE
Participants with at least 30% or at least 50% reduction in pain
no estimate extractedNRVery low
PGIC much or very much improved
no estimate extractedNRVery low
Mean pain intensity at end of study
no estimate extracted3 studies · 93 participantsVery low
Pain no worse than mild at one or two weeks (or equivalent)
no estimate extractedNRVery low
Mean quality of life or "well‐being"
no estimate extracted3 studies · 93 participantsVery low
Participant preference
no estimate extracted2 studies · 52 participantsVery low
Adverse events
no estimate extracted2 studies · 80 participantsVery low
Serious adverse events
no estimate extracted3 studies · 93 participantsVery low