Cochrane · systematic review · CD006601
Codeine, alone and with paracetamol (acetaminophen), for cancer pain
Straube, C, Derry, S, Jackson, KC, et al. · Cochrane Database of Systematic Reviews · 2014 · Cochrane Library
Pain, Palliative and Supportive CareAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
4
No studies
3
Included studies
NR
No studies 3 · 42.9%Ungraded 0 · 0%Very low 4 · 57.1%Low 0 · 0%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Comparison
Population: Adults with cancer pain
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
At least 50% reduction in pain or equivalent | no estimate extracted | 2 studies · 69 participants | Very low |
"Moderate" benefit At least 30% reduction in pain | no estimate extracted | NR | No studies |
Proportion below 30/100 mm on VAS | no estimate extracted | NR | No studies |
Patient Global Impression of Change much or very much improved | no estimate extracted | NR | No studies |
Adverse event withdrawals | no estimate extracted | NR | Very low |
Serious adverse events | no estimate extracted | NR | Very low |
Death | no estimate extracted | NR | Very low |