Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

62 questions · 62 findings · 30 reviews

No studies found 15 · 24.2%GRADE not reported 1 · 1.6%Very low 32 · 51.6%Low 9 · 14.5%Moderate 5 · 8.1%High 0 · 0%

Enhanced recovery protocol vs usual care

Serious adverse events (proportion) · people with major upper gastrointestinal, liver and pancreatic surgery

It is very uncertain whether enhanced recovery protocol changes serious adverse events (proportion) compared with standard care (very low certainty).

1 finding from 1 review

Helium vs carbon dioxide

Pneumoperitoneum‐related serious adverse events · people undergoing laparoscopic general abdominal or gynaecological pelvic surgery under general anaesthesia

It is very uncertain whether helium changes pneumoperitoneum‐related serious adverse events compared with carbon dioxide (very low certainty).

1 finding from 1 review

Laparoscopic fundoplication vs medical management

Serious adverse events · Patients with gastro‐oesophageal reflux disease (GORD) in adults

It is very uncertain whether laparoscopic fundoplication changes serious adverse events compared with medical management (very low certainty).

1 finding from 1 review

Thromboelastography threshold vs standard of care (laboratory parameters)

Serious adverse events measured by plasma transfusion‐related complications within 24 hours № of participants: 21 (1 RCT) · patients undergoing non‐cardiac surgery/invasive procedures

It is very uncertain whether thromboelastography threshold changes serious adverse events measured by plasma transfusion‐related… compared with standard of care (laboratory parameters) (very low certainty).

1 finding from 1 review