Cochrane · systematic review · CD003243

Laparoscopic fundoplication surgery versus medical management for gastro‐oesophageal reflux disease (GORD) in adults

Garg, SK, Gurusamy, KS · Cochrane Database of Systematic Reviews · 2015 · Cochrane Library

GutAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
8
current version
GRADE rated
4
No studies
4
Included studies
NR
No studies 4 · 50%Ungraded 0 · 0%Very low 4 · 50%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Laparoscopic fundoplication versus medical management for gastro‐oesophageal reflux disease (GORD) in adults

Population: Patients with gastro‐oesophageal reflux disease (GORD) in adults
8 questions
OutcomeEffectEvidenceStatus / GRADE
(< 1 year)
Laparoscopic fundoplication vs medical management
no estimate extracted3 studies · 605 participantsVery low
Downgraded: risk of bias, inconsistency
(1 to 5 years)
Laparoscopic fundoplication vs medical management
no estimate extracted2 studies · 323 participantsVery low
Downgraded: risk of bias, inconsistency
Adverse events
Laparoscopic fundoplication vs medical management
no estimate extractedNRNo studies
Serious adverse events
Laparoscopic fundoplication vs medical management
RR 1.46 [1.01, 2.11]2 studies · 637 participantsVery low
Downgraded: risk of bias
Dysphagia
Laparoscopic fundoplication vs medical management
no estimate extractedNRNo studies
(5 years or more)
Laparoscopic fundoplication vs medical management
RR 0.9 [0.57, 1.42]1 study · 228 participantsVery low
Downgraded: risk of bias
Heartburn
Laparoscopic fundoplication vs medical management
no estimate extractedNRNo studies
Reflux
Laparoscopic fundoplication vs medical management
no estimate extractedNRNo studies