What do systematic reviews say?

Manual therapy, prescribed exercises or both vs no intervention or minimal intervention

• Manual therapy and exercise for lateral elbow pain 2024 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 113 participants
  Low

Botulinum toxin vs placebo

• Treatment for sialorrhea (excessive saliva) in people with motor neuron disease/amyotrophic lateral sclerosis 2022 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 17 participants
  Low

Any CNTF vs placebo

• Ciliary neurotrophic factor (CNTF) for amyotrophic lateral sclerosis or motor neuron disease 2004 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 503 participants
  High

Pre-radiotherapy extraction of healthy molar teeth vs Conservative treatment (leaving the teeth in place during radiotherapy, with oral health education and disease prevention: oral hygiene, fluoride, diet advice)

The review found no eligible studies for this question.

• Dental extractions prior to radiotherapy to the jaws for reducing post‐radiotherapy dental complications 2013 · Cochrane All outcomes
  no estimate extracted
  0 studies
  No studies found

Pre-radiotherapy extraction of diseased molar teeth vs Conservative treatment (restoration of the teeth and leaving them in place during radiotherapy, with oral health education and disease prevention: oral hygiene, fluoride, diet advice)

The review found no eligible studies for this question.

• Dental extractions prior to radiotherapy to the jaws for reducing post‐radiotherapy dental complications 2013 · Cochrane All outcomes
  no estimate extracted
  0 studies
  No studies found

CBT vs TRT (directive counselling and bilateral masking)

• Cognitive behavioural therapy for tinnitus 2020 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 42 participants
  Low

Valgus knee brace vs lateral wedge insole

The review found no eligible studies for this question.

• Braces and orthoses for treating osteoarthritis of the knee 2015 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Total thyroidectomy vs subtotal thyroidectomy

The review found no eligible studies for this question.

• Thyroid surgery for Graves’ disease and Graves’ ophthalmopathy 2015 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Early ventilation tubes vs watchful waiting

The review found no eligible studies for this question.

• Ventilation tubes (grommets) for otitis media with effusion (OME) in children 2023 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

CBT vs TRT (directive counselling and bilateral masking)

• Cognitive behavioural therapy for tinnitus 2020 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 42 participants
  Low

Non‐invasive ventilation vs usual care

• Mechanical ventilation for amyotrophic lateral sclerosis/motor neuron disease 2017 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 41 participants
  Low

Non‐invasive ventilation vs usual care

• Mechanical ventilation for amyotrophic lateral sclerosis/motor neuron disease 2017 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 41 participants
  Low

Non‐invasive ventilation vs usual care

The review found no eligible studies for this question.

• Mechanical ventilation for amyotrophic lateral sclerosis/motor neuron disease 2017 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Massage + phonophoresis vs phonophoresis alone

The review found no eligible studies for this question.

• Deep transverse friction massage for treating lateral elbow or lateral knee tendinitis 2014 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Deep transverse massage + physical therapy vs physical therapy alone

The review found no eligible studies for this question.

• Deep transverse friction massage for treating lateral elbow or lateral knee tendinitis 2014 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Massage + ultrasound and placebo ointment vs ultrasound + placebo ointment only

The review found no eligible studies for this question.

• Deep transverse friction massage for treating lateral elbow or lateral knee tendinitis 2014 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Low‐intensity pulsed ultrasound vs control

• Ultrasound and shockwave therapy for acute fractures in adults 2023 · Cochrane Headline outcomes only
  no estimate extracted
  3 studies · 393 participants
  Very low

Conventional occlusion vs atropine penalization

• Conventional occlusion versus pharmacologic penalization for amblyopia 2019 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 256 participants
  Moderate

Risk‐reducing salpingo‐oophorectomy (RRSO) vs no RRSO according to BRCA mutation status

• Risk‐reducing bilateral salpingo‐oophorectomy in women with BRCA1 or BRCA2 mutations 2018 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 98 participants
  Very low

Risk‐reducing salpingo‐oophorectomy (RRSO) vs no RRSO

• Risk‐reducing bilateral salpingo‐oophorectomy in women with BRCA1 or BRCA2 mutations 2018 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 200 participants
  Very low