Cochrane · systematic review · CD012614

Cognitive behavioural therapy for tinnitus

Fuller, T, Cima, R, Langguth, B, et al. · Cochrane Database of Systematic Reviews · 2020 · Cochrane Library

ENTAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
32
current version
GRADE rated
28
No studies
4
Included studies
NR
No studies 4 · 12.5%Ungraded 0 · 0%Very low 4 · 12.5%Low 18 · 56.3%Moderate 6 · 18.8%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

CBT compared to no intervention/waiting list control for tinnitus

Population: adults with tinnitus
8 questions
OutcomeEffectEvidenceStatus / GRADE
Outcomes at end of treatment
CBT vs no intervention/waiting list control
no estimate extractedNRNo studies
Impact of tinnitus on quality of life at treatment end
CBT vs no intervention/waiting list control
no estimate extracted10 studies · 537 participantsLow
Downgraded: risk of bias, inconsistency
Serious adverse effects at end of treatment
CBT vs no intervention/waiting list control
RR 3 [0.13, 69.87]7 studies · 447 participantsModerate
Downgraded: risk of bias
Depression at end of treatment
CBT vs no intervention/waiting list control
no estimate extracted8 studies · 502 participantsLow
Downgraded: risk of bias, inconsistency
Anxiety at end of treatment
CBT vs no intervention/waiting list control
no estimate extracted6 studies · 429 participantsVery low
Downgraded: risk of bias, inconsistency
Health‐related quality of life
CBT vs no intervention/waiting list control
no estimate extracted2 studies · 179 participantsVery low
Downgraded: risk of bias, imprecision
Negatively biased interpretations of tinnitus
CBT vs no intervention/waiting list control
no estimate extracted2 studies · 84 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency
Other adverse effects
CBT vs no intervention/waiting list control
no estimate extracted7 studies · 447 participantsModerate
Downgraded: risk of bias

CBT compared to audiological care (tinnitus education and rehabilitation for hearing loss) for tinnitus

Population: adults with tinnitus
8 questions
OutcomeEffectEvidenceStatus / GRADE
Outcomes at end of treatment
CBT vs audiological care (tinnitus education and rehabilitation
no estimate extractedNRNo studies
Impact of tinnitus on quality of life
CBT vs audiological care (tinnitus education and rehabilitation
no estimate extracted3 studies · 430 participantsModerate
Downgraded: risk of bias
Serious adverse effects
CBT vs audiological care (tinnitus education and rehabilitation
no estimate extracted2 studies · 410 participantsModerate
Downgraded: risk of bias
Depression at end of treatment
CBT vs audiological care (tinnitus education and rehabilitation
no estimate extracted2 studies · 410 participantsLow
Downgraded: risk of bias
Anxiety at end of treatment
CBT vs audiological care (tinnitus education and rehabilitation
no estimate extracted2 studies · 410 participantsLow
Downgraded: risk of bias
Health‐related quality of life
CBT vs audiological care (tinnitus education and rehabilitation
no estimate extracted2 studies · 410 participantsLow
Downgraded: risk of bias
Negatively biased interpretations of tinnitus
CBT vs audiological care (tinnitus education and rehabilitation
no estimate extracted1 study · 336 participantsLow
Downgraded: risk of bias, imprecision
Other adverse effects
CBT vs audiological care (tinnitus education and rehabilitation
no estimate extracted2 studies · 410 participantsModerate
Downgraded: risk of bias

CBT compared to TRT (directive counselling and bilateral masking) for tinnitus

Population: adults with tinnitus
8 questions
OutcomeEffectEvidenceStatus / GRADE
Outcomes at end of treatment
CBT vs TRT (directive counselling and bilateral masking)
no estimate extractedNRNo studies
Impact of tinnitus on quality of life
CBT vs TRT (directive counselling and bilateral masking)
no estimate extracted1 study · 42 participantsLow
Downgraded: risk of bias
Serious adverse effects
CBT vs TRT (directive counselling and bilateral masking)
RR 0.45 [0.04, 4.64]1 study · 42 participantsLow
Downgraded: risk of bias
Depression
CBT vs TRT (directive counselling and bilateral masking)
no estimate extracted1 study · 42 participantsLow
Downgraded: risk of bias
Anxiety
CBT vs TRT (directive counselling and bilateral masking)
no estimate extracted1 study · 42 participantsLow
Downgraded: risk of bias
Health‐related quality of life
CBT vs TRT (directive counselling and bilateral masking)
no estimate extracted1 study · 42 participantsLow
Downgraded: risk of bias
Negatively biased interpretations of tinnitus
CBT vs TRT (directive counselling and bilateral masking)
no estimate extracted1 study · 42 participantsLow
Downgraded: risk of bias
Other adverse effects
CBT vs TRT (directive counselling and bilateral masking)
no estimate extracted1 study · 42 participantsLow
Downgraded: risk of bias

CBT compared to other experimental control for tinnitus

Population: adults with tinnitus
8 questions
OutcomeEffectEvidenceStatus / GRADE
Outcomes at end of treatment
CBT vs other experimental control
no estimate extractedNRNo studies
Impact of tinnitus on quality of life at end of treatment
CBT vs other experimental control
no estimate extracted12 studies · 966 participantsLow
Downgraded: risk of bias, inconsistency
Serious adverse effects
CBT vs other experimental control
RR 1.7 [0.16, 18.36]6 studies · 595 participantsLow
Downgraded: risk of bias, imprecision
Depression at end of treatment
CBT vs other experimental control
no estimate extracted11 studies · 943 participantsLow
Downgraded: risk of bias, imprecision
Anxiety at end of treatment
CBT vs other experimental control
no estimate extracted9 studies · 696 participantsLow
Downgraded: risk of bias, inconsistency
Health‐related quality of life at end of treatment
CBT vs other experimental control
no estimate extracted1 study · 95 participantsVery low
Downgraded: risk of bias, imprecision
Negatively biased interpretations of tinnitus at end of treatment
CBT vs other experimental control
no estimate extracted5 studies · 455 participantsModerate
Downgraded: risk of bias
Other adverse effects
CBT vs other experimental control
no estimate extracted6 studies · 595 participantsLow
Downgraded: risk of bias, imprecision