Cochrane · intervention · CD008857

Dental extractions prior to radiotherapy to the jaws for reducing post‐radiotherapy dental complications

Eliyas, S, Al‐Khayatt, A, Porter, RWJ, et al. · Cochrane Database of Systematic Reviews · 2013 · Cochrane Library

Oral HealthOral and maxillofacial surgery2 versionsAMSTAR 2: not assessed
Full textEvery question was extracted from the full review (methods and results), not only its Summary of Findings table.
Questions
11
current version
GRADE rated
0
No studies
11
Included studies
0
as reported
No studies 11 · 100%Ungraded 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Review question

ElementPlanned (methods)Found (results)
PopulationPatients diagnosed with head and neck cancer planned to undergo any type of radiotherapy (external beam, intensity modulated, image-guided, brachytherapy, conformal, or any other) to the jaws; any age, sex, or socio-economic status; any cancer type, oral hygiene, tobacco, or alcohol status; any radiation dose; unilateral or bilateral; with or without dental maintenanceNo eligible studies identified
InterventionPre-radiotherapy dental extraction (extraction of teeth prior to radiotherapy); extraction of teeth during radiotherapyNo eligible studies identified
ComparisonLeaving teeth in situ/in place during radiotherapy; post-radiotherapy extraction; preventative/conservative treatment (oral hygiene instruction, fluoride, dietary advice, restoration of caries, management of periodontal disease)No eligible studies identified
OutcomesPrimary: development of post-radiotherapy dental complications (caries, fractured teeth, periapical infection, periodontal disease, osteoradionecrosis). Secondary: patients' quality of life; delay in start of radiation treatment; trismus preventing further restorative treatment; overall survivalNo eligible studies identified
Study designsRandomised controlled trials (excluding split-mouth and cross-over trials)No eligible studies identified
TimingNot specifiedNo eligible studies identified

Search date: 2012-11-22. Databases: The Cochrane Oral Health Group's Trials Register; Cochrane Central Register of Controlled Trials (CENTRAL); MEDLINE via OVID; EMBASE via OVID; CANCERLIT via PubMed; Cumulative Index of Nursing and Allied Health Literature (CINAHL) via EBSCO

Questions and results

Show all 2 versions

Pre-radiotherapy extraction of diseased molar teeth vs Conservative treatment (restoration of the teeth and leaving them in place during radiotherapy, with oral health education and disease prevention: oral hygiene, fluoride, diet advice)

Population: Patients diagnosed with head and neck cancer planned to undergo any type of radiotherapy (external beam, intensity modulated, image-guided, brachytherapy, conformal, or any other) to the jaws; any age, sex, or socio-economic status; any cancer type, oral hygiene, tobacco, or alcohol status; any radiation dose; unilateral or bilateral; with or without dental maintenance
5 questions
OutcomeEffectEvidenceStatus / GRADE
Development of post-radiotherapy dental complications (caries, fractured teeth, periapical infection, periodontal disease, osteoradionecrosis)
no estimate extracted0 studiesNo studies
Trismus preventing further restorative treatment
no estimate extracted0 studiesNo studies
Delay in start of radiation treatment
no estimate extracted0 studiesNo studies
Patients' quality of life
no estimate extracted0 studiesNo studies
Overall survival
no estimate extracted0 studiesNo studies

Pre-radiotherapy extraction of healthy molar teeth vs Conservative treatment (leaving the teeth in place during radiotherapy, with oral health education and disease prevention: oral hygiene, fluoride, diet advice)

Population: Patients diagnosed with head and neck cancer planned to undergo any type of radiotherapy (external beam, intensity modulated, image-guided, brachytherapy, conformal, or any other) to the jaws; any age, sex, or socio-economic status; any cancer type, oral hygiene, tobacco, or alcohol status; any radiation dose; unilateral or bilateral; with or without dental maintenance
5 questions
OutcomeEffectEvidenceStatus / GRADE
Overall survival
no estimate extracted0 studiesNo studies
Trismus preventing further restorative treatment
no estimate extracted0 studiesNo studies
Patients' quality of life
no estimate extracted0 studiesNo studies
Delay in start of radiation treatment
no estimate extracted0 studiesNo studies
Development of post-radiotherapy dental complications (caries, fractured teeth, periapical infection, periodontal disease, osteoradionecrosis)
no estimate extracted0 studiesNo studies

Pre-radiotherapy dental extraction vs Post-radiotherapy dental extraction

Population: Patients diagnosed with head and neck cancer planned to undergo any type of radiotherapy (external beam, intensity modulated, image-guided, brachytherapy, conformal, or any other) to the jaws; any age, sex, or socio-economic status; any cancer type, oral hygiene, tobacco, or alcohol status; any radiation dose; unilateral or bilateral; with or without dental maintenance
1 question
OutcomeEffectEvidenceStatus / GRADE
Outcome NR
no estimate extracted0 studiesNo studies