Cochrane · systematic review · CD004427
Mechanical ventilation for amyotrophic lateral sclerosis/motor neuron disease
Radunovic, A, Annane, D, Rafiq, MK, et al. · Cochrane Database of Systematic Reviews · 2017 · Cochrane Library
NeuromuscularAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
5
current version
GRADE rated
3
No studies
2
Included studies
NR
No studies 2 · 40%Ungraded 0 · 0%Very low 0 · 0%Low 2 · 40%Moderate 1 · 20%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Non‐invasive ventilation compared with standard care for amyotrophic lateral sclerosis (ALS)
Population: people with ALS
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Survival Non‐invasive ventilation vs standard care | no estimate extracted | 1 study · 41 participants | Moderate |
Quality of life (SF‐36 MCS) Non‐invasive ventilation vs standard care | no estimate extracted | 1 study · 41 participants | Low Downgraded: risk of bias |
Quality of life (SF‐36 PCS) Non‐invasive ventilation vs standard care | no estimate extracted | NR | No studies |
Quality of life (SAQLI) Non‐invasive ventilation vs standard care | no estimate extracted | 1 study · 41 participants | Low Downgraded: risk of bias |
Adverse events (not reported) Non‐invasive ventilation vs standard care | no estimate extracted | NR | No studies |