It is very uncertain whether myo‐inositol changes adverse event ‐ multiple pregnancy compared with an ovulation induction agent (clomiphene) (very low certainty).
Myo‐inositol showed no clear difference in adverse event ‐ multiple pregnancy compared with placebo, no/standard treatment (low certainty).
It is very uncertain whether myo‐inositol changes adverse event ‐ multiple pregnancy compared with antioxidant (melatonin) (very low certainty).
IUI in stimulated cycles showed no clear difference in multiple pregnancy rate per couple compared with TI (low certainty).
Low‐dose aspirin showed no clear difference in multiple pregnancy (on ultrasound) compared with placebo or no treatment (low certainty).
It is very uncertain whether chinese herbal medicine (CHM) plus follicle aspiration plus… changes multiple pregnancy (adverse events) compared with follicle aspiration plus ovulation induction (very low certainty).
The review found no eligible studies for this question.
It is very uncertain whether ultrasound‐guided transvaginal ovarian needle drilling with… changes multiple pregnancy rate (per woman) compared with gn (very low certainty).
Metformin showed no clear difference in multiple pregnancy rate (per woman) compared with placebo co‐treatment (low certainty).
It is very uncertain whether fresh changes multiple pregnancy rate: cumulatively compared with frozen embryo transfer (cumulatively) (very low certainty).
It is very uncertain whether hCG changes multiple pregnancy rate per pregnancy compared with gnRH‐a (very low certainty).
It is very uncertain whether hCG changes multiple pregnancy rate per pregnancy compared with LH surge (very low certainty).
u‐hCG showed no clear difference in multiple pregnancy rate per pregnancy compared with r‐hCG (low certainty).
The review found no eligible studies for this question.
It is very uncertain whether glucocorticoid supplementation changes multiple pregnancy rate per woman/couple compared with placebo (very low certainty).
Gonadotrophins showed no clear difference in incidence of multiple pregnancy per woman compared with continued clomiphene citrate (moderate certainty).
The review found no eligible studies for this question.
Ultrasound‐guided embryo transfer showed no clear difference in multiple pregnancy (per woman randomised) compared with clinical touch (moderate certainty).
Combined oral contraceptive pill showed no clear difference in multiple pregnancy rate (COCP + Ant vs Ant) compared with no pretreatment (low certainty).
Recombinant follicle stimulating hormone showed no clear difference in incidence of multiple pregnancy (per woman) compared with urinary‐derived gonadotrophins (low certainty).