Cochrane · systematic review · CD008583

Ultrasound-guided transvaginal ovarian needle drilling for clomiphene-resistant polycystic ovarian syndrome in subfertile women

Zhang Jing, Tang Liulin, Kong Linglingli, et al. · Cochrane Database of Systematic Reviews · 2019 · Cochrane Library

Gynaecology and FertilityAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
5
No studies
2
Included studies
NR
No studies 2 · 28.6%Ungraded 0 · 0%Very low 5 · 71.4%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Ultrasound‐guided transvaginal ovarian needle drilling with gonadotropin (Gn) compared to Gn for clomiphene‐resistant polycystic ovarian syndrome in subfertile women

Population: clomiphene‐resistant polycystic ovarian syndrome in subfertile women
7 questions
OutcomeEffectEvidenceStatus / GRADE
Live birth rate (per woman)
Ultrasound‐guided transvaginal ovarian needle drilling with gonadotropin (Gn) vs Gn
no estimate extractedNRNo studies
Incidence of surgical complications (per woman)
Ultrasound‐guided transvaginal ovarian needle drilling with gonadotropin (Gn) vs Gn
no estimate extractedNRNo studies
Pregnancy rate (per woman)
Ultrasound‐guided transvaginal ovarian needle drilling with gonadotropin (Gn) vs Gn
OR 3.29 [1.43, 7.54]2 studies · 166 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency
Ovulation rate (per woman)
Ultrasound‐guided transvaginal ovarian needle drilling with gonadotropin (Gn) vs Gn
OR 3.02 [0.75, 12.2]1 study · 92 participantsVery low
Downgraded: risk of bias, imprecision
Incidence of OHSS (per woman)
Ultrasound‐guided transvaginal ovarian needle drilling with gonadotropin (Gn) vs Gn
OR 0.13 [0.01, 2.64]2 studies · 155 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency
Miscarriage rate (per woman)
Ultrasound‐guided transvaginal ovarian needle drilling with gonadotropin (Gn) vs Gn
OR 0.56 [0.03, 10.93]1 study · 16 participantsVery low
Downgraded: risk of bias, imprecision
Multiple pregnancy rate (per woman)
Ultrasound‐guided transvaginal ovarian needle drilling with gonadotropin (Gn) vs Gn
OR 1.25 [0.27, 5.77]2 studies · 155 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency