Cochrane · systematic review · CD007535

Chinese herbal medicine for subfertile women with polycystic ovarian syndrome

Zhou, K, Zhang, J, Xu, L, et al. · Cochrane Database of Systematic Reviews · 2021 · Cochrane Library

Gynaecology and Fertility2 versionsAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
14
current version
GRADE rated
7
No studies
7
Included studies
NR
No studies 7 · 50%Ungraded 0 · 0%Very low 6 · 42.9%Low 1 · 7.1%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Show all 2 versions

Chinese herbal medicine (CHM) versus clomiphene for subfertile women with PCOS

Population: subfertile women with PCOS
3 questions
OutcomeEffectEvidenceStatus / GRADE
Live birth rate
Chinese herbal medicine (CHM) vs clomiphene
no estimate extractedNRNo studies
Pregnancy rate
Chinese herbal medicine (CHM) vs clomiphene
OR 1.41 [0.63, 3.19]3 studies · 140 participantsVery low
Downgraded: risk of bias, imprecision
Adverse effects
Chinese herbal medicine (CHM) vs clomiphene
no estimate extractedNRNo studies

Chinese herbal medicine (CHM) plus clomiphene versus clomiphene for subfertile women with PCOS

Population: subfertile women with PCOS
3 questions
OutcomeEffectEvidenceStatus / GRADE
Live birth
Chinese herbal medicine (CHM) plus clomiphene vs clomiphene
no estimate extractedNRNo studies
Pregnancy rate (per woman)
Chinese herbal medicine (CHM) plus clomiphene vs clomiphene
OR 3.06 [2.05, 4.55]6 studies · 470 participantsLow
Downgraded: risk of bias, imprecision
Adverse events
Chinese herbal medicine (CHM) plus clomiphene vs clomiphene
no estimate extractedNRNo studies

Chinese herbal medicine (CHM) plus follicle aspiration plus ovulation induction versus follicle aspiration plus ovulation induction for subfertile women with PCOS

Population: subfertile women with PCOS
5 questions
OutcomeEffectEvidenceStatus / GRADE
Live birth
Chinese herbal medicine (CHM) plus follicle aspiration plus ovulation induction vs follicle aspiration plus ovulation induction
no estimate extractedNRNo studies
Pregnancy rate
Chinese herbal medicine (CHM) plus follicle aspiration plus ovulation induction vs follicle aspiration plus ovulation induction
OR 1.62 [0.46, 5.68]1 study · 44 participantsVery low
Downgraded: risk of bias, imprecision
Luteinised unruptured follicle syndrome (adverse events)
Chinese herbal medicine (CHM) plus follicle aspiration plus ovulation induction vs follicle aspiration plus ovulation induction
Peto OR 0.6 [0.06, 6.14]1 study · 44 participantsVery low
Downgraded: risk of bias, imprecision
Ovarian hyperstimulation syndrome (adverse events)
Chinese herbal medicine (CHM) plus follicle aspiration plus ovulation induction vs follicle aspiration plus ovulation induction
Peto OR 0.16 [0, 8.19]1 study · 44 participantsVery low
Downgraded: risk of bias, imprecision
Multiple pregnancy (adverse events)
Chinese herbal medicine (CHM) plus follicle aspiration plus ovulation induction vs follicle aspiration plus ovulation induction
Peto OR 0.6 [0.06, 6.14]1 study · 44 participantsVery low
Downgraded: risk of bias, imprecision

Chinese herbal medicine (CHM) plus laparoscopic ovarian drilling (LOD) versus LOD for subfertile women with PCOS

Population: subfertile women with PCOS
3 questions
OutcomeEffectEvidenceStatus / GRADE
Live birth
Chinese herbal medicine (CHM) plus laparoscopic ovarian drilling (LOD) vs LOD
no estimate extractedNRNo studies
Pregnancy rate (per woman)
Chinese herbal medicine (CHM) plus laparoscopic ovarian drilling (LOD) vs LOD
OR 3.5 [0.72, 17.09]1 study · 30 participantsVery low
Downgraded: risk of bias, imprecision
Adverse events
Chinese herbal medicine (CHM) plus laparoscopic ovarian drilling (LOD) vs LOD
no estimate extractedNRNo studies