Cochrane · systematic review · CD007535
Chinese herbal medicine for subfertile women with polycystic ovarian syndrome
Zhou, K, Zhang, J, Xu, L, et al. · Cochrane Database of Systematic Reviews · 2021 · Cochrane Library
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
14
current version
GRADE rated
7
No studies
7
Included studies
NR
No studies 7 · 50%Ungraded 0 · 0%Very low 6 · 42.9%Low 1 · 7.1%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Current version onlyChinese herbal medicine (CHM) versus clomiphene for subfertile women with PCOS
Population: subfertile women with PCOS
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Live birth rate Chinese herbal medicine (CHM) vs clomiphene | no estimate extracted | NR | No studies |
Pregnancy rate Chinese herbal medicine (CHM) vs clomiphene | OR 1.41 [0.63, 3.19] | 3 studies · 140 participants | Very low Downgraded: risk of bias, imprecision |
Adverse effects Chinese herbal medicine (CHM) vs clomiphene | no estimate extracted | NR | No studies |
Chinese herbal medicine (CHM) plus clomiphene versus clomiphene for subfertile women with PCOS
Population: subfertile women with PCOS
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Live birth Chinese herbal medicine (CHM) plus clomiphene vs clomiphene | no estimate extracted | NR | No studies |
Pregnancy rate (per woman) Chinese herbal medicine (CHM) plus clomiphene vs clomiphene | OR 3.06 [2.05, 4.55] | 6 studies · 470 participants | Low Downgraded: risk of bias, imprecision |
Adverse events Chinese herbal medicine (CHM) plus clomiphene vs clomiphene | no estimate extracted | NR | No studies |
Chinese herbal medicine (CHM) plus follicle aspiration plus ovulation induction versus follicle aspiration plus ovulation induction for subfertile women with PCOS
Population: subfertile women with PCOS
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Live birth Chinese herbal medicine (CHM) plus follicle aspiration plus ovulation induction vs follicle aspiration plus ovulation induction | no estimate extracted | NR | No studies |
Pregnancy rate Chinese herbal medicine (CHM) plus follicle aspiration plus ovulation induction vs follicle aspiration plus ovulation induction | OR 1.62 [0.46, 5.68] | 1 study · 44 participants | Very low Downgraded: risk of bias, imprecision |
Luteinised unruptured follicle syndrome (adverse events) Chinese herbal medicine (CHM) plus follicle aspiration plus ovulation induction vs follicle aspiration plus ovulation induction | Peto OR 0.6 [0.06, 6.14] | 1 study · 44 participants | Very low Downgraded: risk of bias, imprecision |
Ovarian hyperstimulation syndrome (adverse events) Chinese herbal medicine (CHM) plus follicle aspiration plus ovulation induction vs follicle aspiration plus ovulation induction | Peto OR 0.16 [0, 8.19] | 1 study · 44 participants | Very low Downgraded: risk of bias, imprecision |
Multiple pregnancy (adverse events) Chinese herbal medicine (CHM) plus follicle aspiration plus ovulation induction vs follicle aspiration plus ovulation induction | Peto OR 0.6 [0.06, 6.14] | 1 study · 44 participants | Very low Downgraded: risk of bias, imprecision |
Chinese herbal medicine (CHM) plus laparoscopic ovarian drilling (LOD) versus LOD for subfertile women with PCOS
Population: subfertile women with PCOS
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Live birth Chinese herbal medicine (CHM) plus laparoscopic ovarian drilling (LOD) vs LOD | no estimate extracted | NR | No studies |
Pregnancy rate (per woman) Chinese herbal medicine (CHM) plus laparoscopic ovarian drilling (LOD) vs LOD | OR 3.5 [0.72, 17.09] | 1 study · 30 participants | Very low Downgraded: risk of bias, imprecision |
Adverse events Chinese herbal medicine (CHM) plus laparoscopic ovarian drilling (LOD) vs LOD | no estimate extracted | NR | No studies |
Chinese herbal medicine (CHM) versus clomiphene for subfertile women with polycystic ovarian syndrome (PCOS)
Population: subfertile women with PCOS
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Live birth rate Chinese herbal medicine (CHM) vs clomiphene | no estimate extracted | NR | No studies |
Pregnancy rate Chinese herbal medicine (CHM) vs clomiphene | OR 1.98 [0.78, 5.06] | 2 studies · 90 participants | Very low Downgraded: risk of bias, imprecision |
Adverse effects Chinese herbal medicine (CHM) vs clomiphene | no estimate extracted | NR | No studies |
Chinese herbal medicine (CHM) + clomiphene versus clomiphene for subfertile women with polycystic ovarian syndrome (PCOS)
Population: subfertile women with PCOS
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Live birth Chinese herbal medicine (CHM) + clomiphene vs clomiphene | no estimate extracted | NR | No studies |
Pregnancy rate (per woman) Chinese herbal medicine (CHM) + clomiphene vs clomiphene | OR 2.62 [1.65, 4.14] | 3 studies · 300 participants | Low Downgraded: risk of bias, imprecision |
Adverse events Chinese herbal medicine (CHM) + clomiphene vs clomiphene | no estimate extracted | NR | No studies |
Chinese herbal medicine (CHM) + follicle aspiration + ovulation induction versus follicle aspiration + ovulation induction for subfertile women with polycystic ovarian syndrome (PCOS)
Population: subfertile women with PCOS
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Live birth Chinese herbal medicine (CHM) + follicle aspiration + ovulation induction vs follicle aspiration + ovulation induction | no estimate extracted | NR | No studies |
Pregnancy rate Chinese herbal medicine (CHM) + follicle aspiration + ovulation induction vs follicle aspiration + ovulation induction | OR 1.6 [0.46, 5.52] | 1 study · 44 participants | Very low Downgraded: risk of bias, imprecision |
Luteinized unruptured follicle syndrome (adverse events) Chinese herbal medicine (CHM) + follicle aspiration + ovulation induction vs follicle aspiration + ovulation induction | OR 0.6 [0.06, 6.14] | 1 study · 44 participants | Very low Downgraded: risk of bias, imprecision |
Ovarian hyperstimulation syndrome (adverse events) Chinese herbal medicine (CHM) + follicle aspiration + ovulation induction vs follicle aspiration + ovulation induction | OR 0.16 [0, 8.19] | 1 study · 44 participants | Very low Downgraded: risk of bias, imprecision |
Multiple pregnancy (adverse events) Chinese herbal medicine (CHM) + follicle aspiration + ovulation induction vs follicle aspiration + ovulation induction | OR 0.6 [0.06, 6.14] | 1 study · 44 participants | Very low Downgraded: risk of bias, imprecision |
Chinese herbal medicine (CHM) + laparoscopic ovarian drilling (LOD) versus LOD for subfertile women with polycystic ovarian syndrome (PCOS)
Population: subfertile women with PCOS
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Live birth Chinese herbal medicine (CHM) + laparoscopic ovarian drilling (LOD) vs LOD | no estimate extracted | NR | No studies |
Pregnancy rate (per woman) Chinese herbal medicine (CHM) + laparoscopic ovarian drilling (LOD) vs LOD | OR 3.5 [0.72, 17.09] | 1 study · 30 participants | Very low Downgraded: risk of bias, imprecision |
Adverse events Chinese herbal medicine (CHM) + laparoscopic ovarian drilling (LOD) vs LOD | no estimate extracted | NR | No studies |