Cochrane · systematic review · CD004832

Aspirin for in vitro fertilisation

Siristatidis, CS, Basios, G, Pergialiotis, V, et al. · Cochrane Database of Systematic Reviews · 2016 · Cochrane Library

Gynaecology and Fertility2 versionsAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
6
No studies
1
Included studies
NR
No studies 1 · 14.3%Ungraded 0 · 0%Very low 2 · 28.6%Low 2 · 28.6%Moderate 2 · 28.6%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Show all 2 versions

Low‐dose aspirin compared to placebo or no treatment for women undergoing ART

Population: Women with subfertility
7 questions
OutcomeEffectEvidenceStatus / GRADE
Live birth
Low‐dose aspirin vs placebo or no treatment
RR 0.91 [0.72, 1.15]3 studies · 1053 participantsModerate
Downgraded: imprecision
Clinical pregnancy
Low‐dose aspirin vs placebo or no treatment
RR 1.03 [0.91, 1.17]10 studies · 2142 participantsModerate
Downgraded: risk of bias
Multiple pregnancy (on ultrasound)
Low‐dose aspirin vs placebo or no treatment
RR 0.67 [0.37, 1.25]2 studies · 656 participantsLow
Downgraded: imprecision
Miscarriage rate per woman
Low‐dose aspirin vs placebo or no treatment
RR 1.1 [0.68, 1.77]5 studies · 1497 participantsLow
Downgraded: imprecision
Ectopic pregnancy
Low‐dose aspirin vs placebo or no treatment
RR 1.86 [0.75, 4.63]3 studies · 1135 participantsVery low
Downgraded: risk of bias, imprecision
Vaginal bleeding
Low‐dose aspirin vs placebo or no treatment
RR 1.01 [0.14, 7.13]1 study · 487 participantsVery low
Downgraded: risk of bias, imprecision
Other adverse events
Low‐dose aspirin vs placebo or no treatment
no estimate extractedNRNo studies