Findings

What do systematic reviews say?

17 questions · 17 findings · 13 reviews · Hepato-Biliary

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No studies found 2 · 11.8%GRADE not reported 0 · 0%Very low 13 · 76.5%Low 2 · 11.8%Moderate 0 · 0%High 0 · 0%

Summary of findings table ‐ Intraperitoneal local anaesthetic vs control

All‐cause mortality · people undergoing laparoscopic cholecystectomy.

1 finding from 1 review

Intraperitoneal local anaesthetic instillation versus no intraperitoneal local anaesthetic instillation for… 2021 · Cochrane Headline outcomes only
no estimate extracted
8 studies · 446 participants
Very low

Low‐pressure vs standard pressure pneumoperitoneum

All‐cause mortality · patients with laparoscopic cholecystectomy.

1 finding from 1 review

Low pressure versus standard pressure pneumoperitoneum in laparoscopic cholecystectomy 2014 · Cochrane Headline outcomes only
no estimate extracted
8 studies · 434 participants
Very low

Infiltration injection local anaesthetic vs no local anaesthetic wound infiltration

All‐cause mortality · patients with people undergoing laparoscopic cholecystectomy.

1 finding from 1 review

Wound infiltration with local anaesthetic agents for laparoscopic cholecystectomy 2014 · Cochrane Headline outcomes only
no estimate extracted
7 studies · 539 participants
Very low

Local anaesthetic wound infiltration before incision vs end of surgery

All‐cause mortality · patients with people undergoing laparoscopic cholecystectomy

1 finding from 1 review

Wound infiltration with local anaesthetic agents for laparoscopic cholecystectomy 2014 · Cochrane Headline outcomes only
no estimate extracted
1 study · 43 participants
Very low

Intervention not reported

Mortality · people undergoing laparoscopic cholecystectomy.

1 finding from 1 review

Wound infiltration with local anaesthetic agents for laparoscopic cholecystectomy 2014 · Cochrane Headline outcomes only
no estimate extracted
1 study · 137 participants
Very low

Fewer‐than‐four ports vs four ports

All‐cause mortality · people undergoing laparoscopic cholecystectomy.

1 finding from 1 review

Fewer‐than‐four ports versus four ports for laparoscopic cholecystectomy 2014 · Cochrane Headline outcomes only
no estimate extracted
7 studies · 634 participants
Very low

Various interventions vs control

All‐cause mortality · people undergoing laparoscopic cholecystectomy.

1 finding from 1 review

Pharmacological interventions for prevention or treatment of postoperative pain in people undergoing laparoscopic… 2014 · Cochrane Headline outcomes only
no estimate extracted
1 study · 123 participants
Very low

Intervention not reported

Mortality · people undergoing laparoscopic cholecystectomy

1 finding from 1 review

Methods of intraperitoneal local anaesthetic instillation for laparoscopic cholecystectomy 2014 · Cochrane Headline outcomes only
no estimate extracted
1 study · 206 participants
Very low

Supplementary box model training vs standard training

All‐cause mortality · surgical trainees with limited prior laparoscopic experience

1 finding from 1 review

Laparoscopic surgical box model training for surgical trainees with limited prior laparoscopic experience 2014 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 168 participants
Very low

Early vs delayed laparoscopic cholecystectomy

All‐cause mortality · people with acute cholecystitis.

1 finding from 1 review

Early versus delayed laparoscopic cholecystectomy for people with acute cholecystitis 2013 · Cochrane Headline outcomes only
no estimate extracted
5 studies · 438 participants
Very low

Routine abdominal drain vs No drain

All‐cause mortality · patients with laparoscopic cholecystectomy.

It is very uncertain whether routine abdominal drain changes mortality compared with 'no drain' (very low certainty).

1 finding from 1 review

Routine abdominal drainage versus no abdominal drainage for uncomplicated laparoscopic cholecystectomy 2013 · Cochrane Headline outcomes only
RR 0.41 [0.04, 4.37]
10 studies · 1681 participants
Very low

Early vs delayed laparoscopic cholecystectomy

All‐cause mortality · people with biliary colic

It is very uncertain whether early changes mortality compared with delayed laparoscopic cholecystectomy (very low certainty).

1 finding from 1 review

Early versus delayed laparoscopic cholecystectomy for uncomplicated biliary colic 2013 · Cochrane Headline outcomes only
RR 0.38 [0.02, 9.03]
1 study · 75 participants
Very low

Day‐surgery vs overnight stay surgery

Short term mortality · patients with laparoscopic cholecystectomy.

1 finding from 1 review

Day‐surgery versus overnight stay surgery for laparoscopic cholecystectomy 2013 · Cochrane Headline outcomes only
no estimate extracted
1 study · 86 participants
Low

Summary of findings table ‐ Deep neuromuscular blockade (NMB) vs moderate NMB

All‐cause mortality short‐term · adults undergoing intra‐ and transperitoneal laparoscopic procedures

It is very uncertain whether summary of findings table ‐ Deep neuromuscular blockade (NMB) changes all‐cause mortality short‐term compared with moderate NMB (very low certainty).

1 finding from 1 review

Deep neuromuscular blockade in adults undergoing an abdominal laparoscopic procedure 2024 · Cochrane Headline outcomes only
Peto OR 7.22 [0.45, 115.43]
12 studies · 1390 participants
Very low

Summary of findings table ‐ Deep neuromuscular blockade (NMB) vs shallow NMB

All‐cause mortality ‐ not reported · adults undergoing intra‐ and transperitoneal laparoscopic procedures

The review found no eligible studies for this question.

1 finding from 1 review

Deep neuromuscular blockade in adults undergoing an abdominal laparoscopic procedure 2024 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of findings table ‐ Deep neuromuscular blockade (NMB) vs no NMB

All‐cause mortality start of surgery ‐ not reported · adults undergoing intra‐ and transperitoneal laparoscopic procedures

The review found no eligible studies for this question.

1 finding from 1 review

Deep neuromuscular blockade in adults undergoing an abdominal laparoscopic procedure 2024 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Overall mortality (30‐day postoperative; procedure‐ and non‐procedure related) · patients with stones in the gallbladder and common bile duct undergoing laparoscopic cholecystectomy

1 finding from 1 review

Laparoscopic‐endoscopic rendezvous versus preoperative endoscopic sphincterotomy in people undergoing laparoscopic… 2018 · Cochrane Headline outcomes only
no estimate extracted
5 studies · 516 participants
Low