Cochrane · systematic review · CD007337
Intraperitoneal local anaesthetic instillation versus no intraperitoneal local anaesthetic instillation for laparoscopic cholecystectomy
Rutherford, D, Massie, EM, Worsley, C, et al. · Cochrane Database of Systematic Reviews · 2021 · Cochrane Library
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
6
No studies
1
Included studies
NR
No studies 1 · 14.3%Ungraded 0 · 0%Very low 3 · 42.9%Low 2 · 28.6%Moderate 1 · 14.3%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Show all 2 versionsSummary of findings table ‐ Intraperitoneal local anaesthetic compared to control for patients undergoing laparoscopic cholecystectomy
Population: patients undergoing laparoscopic cholecystectomy
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Mortality Summary of findings table ‐ Intraperitoneal local anaesthetic vs control | no estimate extracted | 8 studies · 446 participants | Very low Downgraded: risk of bias, imprecision |
Serious adverse events Summary of findings table ‐ Intraperitoneal local anaesthetic vs control | RR 1.07 [0.49, 2.34] | 13 studies · 988 participants | Very low Downgraded: risk of bias, imprecision |
Health related quality of life ‐ not measured Summary of findings table ‐ Intraperitoneal local anaesthetic vs control | no estimate extracted | NR | No studies |
Hospital stay Summary of findings table ‐ Intraperitoneal local anaesthetic vs control | no estimate extracted | 12 studies · 936 participants | Moderate Downgraded: risk of bias |
Proportion discharged as day surgery Summary of findings table ‐ Intraperitoneal local anaesthetic vs control | RR 1.43 [0.64, 3.2] | 3 studies · 242 participants | Very low Downgraded: risk of bias, imprecision, inconsistency |
Pain (4 to 8 hours)Scale from: 1 to 10 Summary of findings table ‐ Intraperitoneal local anaesthetic vs control | no estimate extracted | 57 studies · 4046 participants | Low Downgraded: risk of bias, inconsistency |
Pain (9 to 24 hours)Scale from: 1 to 10 Summary of findings table ‐ Intraperitoneal local anaesthetic vs control | no estimate extracted | 52 studies · 3588 participants | Low Downgraded: risk of bias, inconsistency |