Vitamin C vs placebo
Adverse events · healthy male physicians, period: 1997 to 2007 and female health professionals, period: 1998 to 2005
1 finding from 1 review
- no estimate extracted1 study · 1 participantsHigh
Findings
What do systematic reviews say?
73 questions · 73 findings · 34 reviews
No studies found 19 · 26%GRADE not reported 2 · 2.7%Very low 15 · 20.5%Low 15 · 20.5%Moderate 13 · 17.8%High 9 · 12.3%
Vitamin D vs placebo or no intervention
Adverse events ‐ Nephrolithiasis in trials using vitamin D3 combined with calcium · healthy participants or recruited among the general population; individuals diagnosed with a specific disease in a stable phase or with…
Vitamin D may leads to higher adverse events: nephrolithiasis in trials using vitamin… compared with placebo or no intervention (low certainty).
1 finding from 1 review
- RR 1.17 [1.03, 1.34]3 studies · 42753 participantsLow
Vitamin C vs allopurinol
Total adverse events · participants with chronic gout and sUA level > 0.36mmol/L
1 finding from 1 review
- no estimate extracted1 study · 40 participantsLow
Vitamin C vs allopurinol
Withdrawals due to adverse events · participants with chronic gout and sUA level > 0.36mmol/L
1 finding from 1 review
- no estimate extracted1 study · 40 participantsLow
Vitamin C vs placebo
Adverse events · adults and children with exercise‐induced bronchoconstriction/asthma
The review found no eligible studies for this question.
1 finding from 1 review
- Vitamin C for asthma and exercise‐induced bronchoconstriction 2013 · Cochrane Headline outcomes onlyno estimate extractedStudies not reportedNo studies found
Vitamin C vs placebo
Adverse events · people with asthma
1 finding from 1 review
- Vitamin C for asthma and exercise‐induced bronchoconstriction 2013 · Cochrane Headline outcomes onlyno estimate extracted1 study · 41 participantsVery low
hAMMSC‐CM + vitamin C vs hAMMSC‐CM
Adverse events associated with treatment · ulceration caused by nerve damage in leprosy
1 finding from 1 review
- Interventions for ulceration and other skin changes caused by nerve damage in leprosy 2019 · Cochrane Headline outcomes onlyno estimate extracted1 study · 44 participantsVery low
Vitamin K vs control
Adverse events · adults and children with cystic fibrosis
The review found no eligible studies for this question.
1 finding from 1 review
- no estimate extractedStudies not reportedNo studies found
Vitamin D vs placebo
Adverse events · people with sickle cell disease
Vitamin D showed no clear difference in adverse events compared with placebo (low certainty).
1 finding from 1 review
- RR 3.16 [0.14, 72.84]1 study · 37 participantsLow
Vitamin D vs placebo
Serious adverse events · premenopausal women (age 18–32.7 years)
The review found no eligible studies for this question.
1 finding from 1 review
- Calcium and vitamin D for increasing bone mineral density in premenopausal women 2023 · Cochrane Headline outcomes onlyno estimate extractedStudies not reportedNo studies found
Vitamin D vs placebo or no intervention
Serious adverse events · people with chronic liver diseases
1 finding from 1 review
- Vitamin D supplementation for chronic liver diseases in adults 2021 · Cochrane Headline outcomes onlyno estimate extractedStudies not reportedVery low
Vitamin D vs placebo or no intervention
Non‐serious adverse events · people with chronic liver diseases
1 finding from 1 review
- Vitamin D supplementation for chronic liver diseases in adults 2021 · Cochrane Headline outcomes onlyno estimate extractedStudies not reportedVery low
Vitamin D vs placebo
Adverse events · people with diabetes and foot ulcers
The review found no eligible studies for this question.
1 finding from 1 review
- Nutritional interventions for treating foot ulcers in people with diabetes 2020 · Cochrane Headline outcomes onlyno estimate extractedStudies not reportedNo studies found
150,000 IU of vitamin D vs 300,000 IU of vitamin D
Adverse events · people with diabetes and foot ulcers
The review found no eligible studies for this question.
1 finding from 1 review
- Nutritional interventions for treating foot ulcers in people with diabetes 2020 · Cochrane Headline outcomes onlyno estimate extractedStudies not reportedNo studies found
Acupuncture plus NSAID plus vitamins vs NSAID plus vitamins
Adverse events · carpal tunnel syndrome
The review found no eligible studies for this question.
1 finding from 1 review
- Acupuncture and related interventions for the treatment of symptoms associated with carpal tunnel syndrome 2018 · Cochrane Headline outcomes onlyno estimate extractedStudies not reportedNo studies found
Vitamin D plus calcium vs vitamin D
Adverse events (number) Asymptomatic hypercalcaemia and hypercalciuria
It is very uncertain whether vitamin D plus calcium changes adverse events (number) Definition: asymptomatic hypercalcaemia and… compared with vitamin D (very low certainty).
1 finding from 1 review
- Vitamin D, calcium or a combination of vitamin D and calcium for the treatment of nutritional rickets in children 2020 · Cochrane Headline outcomes onlyRR 4.76 [0.24, 93.19]1 study · 39 participantsVery low
Vitamin D 100,000 IU/month vs 12,000 IU/month
Adverse events · people with sickle cell disease
1 finding from 1 review
- no estimate extracted1 study · 62 participantsLow
Low‐level laser therapy, wrist splint, and vitamin B6 vs placebo, wrist splint, and vitamin B6
Adverse events · carpal tunnel syndrome
The review found no eligible studies for this question.
1 finding from 1 review
- no estimate extractedStudies not reportedNo studies found
Vitamin E vs placebo
Adverse events: haemorrhagic stroke · healthy people
Vitamin E leads to higher adverse events: haemorrhagic stroke compared with placebo (high certainty).
1 finding from 1 review
- HR 1.74 [1.04, 2.91]1 study · 14641 participantsHigh
Vitamin A vs placebo
Adverse events: yellowing of the skin · healthy people and healthy male physicians
Vitamin A leads to higher adverse events: yellowing of the skin compared with placebo (high certainty).
1 finding from 1 review
- RR 1.14 [1.07, 1.21]1 study · 22071 participantsHigh