Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

24 questions · 24 findings · 12 reviews · Anaesthesia

No studies found 4 · 16.7%GRADE not reported 3 · 12.5%Very low 5 · 20.8%Low 10 · 41.7%Moderate 2 · 8.3%High 0 · 0%

Epidural analgesia vs intravenous patient‐controlled analgesia

Adverse events (assessed at any time during · adults having abdominal surgery

Epidural analgesia showed no clear difference in adverse events (assessed at any time during compared with intravenous patient‐controlled analgesia (low certainty).

1 finding from 1 review

Propofol vs sevoflurane

Adverse event ‐ haemodynamic changes, number of events · patients with rapid emergence from anaesthesia after undergoing brain tumour surgery

Propofol may leads to higher adverse event ‐ haemodynamic changes, number of events compared with sevoflurane (low certainty).

1 finding from 1 review

rHuEPO with iron vs control treatment with or without iron

Adverse events (number of participants with any adverse event) · adult participants, irrespective of gender and type of non‐cardiac surgery, with mild or severe preoperative anaemia

rHuEPO with iron showed no clear difference in adverse events (number of participants with any adverse event) compared with control treatment with or without iron (moderate certainty).

1 finding from 1 review

Topical anaesthesia plus intracameral lidocaine vs topical anaesthesia alone

Intraoperative adverse surgical events attributable to choice of anaesthesia · adults undergoing phacoemulsification cataract surgery

Topical anaesthesia plus intracameral lidocaine showed no clear difference in intraoperative adverse surgical events attributable to choice of… compared with topical anaesthesia alone (low certainty).

1 finding from 1 review

Intervention not reported

Adverse events (Re‐operation for bleeding (reoperation for major bleeding within 30 days (yes/no))) · adults undergoing surgery

It is very uncertain whether the intervention changes adverse events (Re‐operation for bleeding (reoperation for major… (very low certainty).

1 finding from 1 review

Summary of findings ‐ Erector spinae plane block vs serratus anterior plane block

Rates of block‐related adverse events · adults undergoing surgery with general anaesthesia

Summary of findings ‐ Erector spinae plane block showed no clear difference in rates of block‐related adverse events compared with serratus anterior plane block (low certainty).

1 finding from 1 review

Summary of findings ‐ Erector spinae plane block vs intercostal nerve block

Rates of block‐related adverse events · adults undergoing surgery with general anaesthesia

It is very uncertain whether summary of findings ‐ Erector spinae plane block changes rates of block‐related adverse events compared with intercostal nerve block (very low certainty).

1 finding from 1 review