Cochrane · systematic review · CD005276
Topical anaesthesia plus intracameral lidocaine versus topical anaesthesia alone for phacoemulsification cataract surgery in adults
Minakaran, N, Ezra, DG, Allan, BDS · Cochrane Database of Systematic Reviews · 2020 · Cochrane Library
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
7
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 0 · 0%Low 3 · 42.9%Moderate 4 · 57.1%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Show all 2 versionsTopical anaesthesia plus intracameral lidocaine versus topical anaesthesia alone for phacoemulsification cataract surgery in adults
Population: adults undergoing phacoemulsification cataract surgery
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Intraoperative pain or discomfort (continuous data) Topical anaesthesia plus intracameral lidocaine vs topical anaesthesia alone | no estimate extracted | NR | Moderate Downgraded: risk of bias |
Intraoperative pain or discomfort (dichotomous data) Topical anaesthesia plus intracameral lidocaine vs topical anaesthesia alone | OR 0.4 [0.29, 0.57] | NR | Moderate Downgraded: risk of bias, imprecision, inconsistency |
Postoperative pain or discomfort Topical anaesthesia plus intracameral lidocaine vs topical anaesthesia alone | no estimate extracted | NR | Moderate Downgraded: risk of bias, imprecision, indirectness |
Participant satisfaction Topical anaesthesia plus intracameral lidocaine vs topical anaesthesia alone | no estimate extracted | NR | Low Downgraded: risk of bias |
Need for additional anaesthesia during surgery Assessed dichotomously, as 'additional anaesthesia given' or 'additional anaesthesia not given' Topical anaesthesia plus intracameral lidocaine vs topical anaesthesia alone | OR 0.88 [0.56, 1.39] | NR | Low Downgraded: risk of bias, imprecision, inconsistency |
Measures relating to possible intraocular toxicityAssessed by mean percentage change in corneal endothelial cell count from pre‐ to postoperatively in operated eye Assessed from 1 month to 1 year postoperatively Topical anaesthesia plus intracameral lidocaine vs topical anaesthesia alone | no estimate extracted | NR | Moderate Downgraded: imprecision |
Intraoperative adverse surgical events attributable to choice of anaesthesia Topical anaesthesia plus intracameral lidocaine vs topical anaesthesia alone | OR 1 [0.32, 3.16] | NR | Low Downgraded: risk of bias, imprecision, inconsistency |