Question · asked by 1 review
rHuEPO with iron vs control treatment with or without iron: Adverse events (number of participants with any adverse event)
- Population
- adult participants, irrespective of gender and type of non‐cardiac surgery, with mild or severe preoperative anaemia
- Intervention
- rHuEPO with iron
- Comparison
- control treatment with or without iron
- Outcome
- Adverse events (number of participants with any adverse event)
rHuEPO with iron showed no clear difference in adverse events (number of participants with any adverse event) compared with control treatment with or without iron (moderate certainty).
What each review found
Include earlier review versions| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
rHuEPO with iron vs control treatment with or without iron Adverse events (number of participants with any adverse event) · adult participants, irrespective of gender and type of non‐cardiac surgery, with mild or severe preoperative anaemia rHuEPO with iron showed no clear difference in adverse events (number of participants with any adverse event) compared with control treatment with or without iron (moderate certainty). Erythropoietin plus iron versus control treatment including placebo or iron for preoperative anaemic adults… (2020) · Cochrane Headline outcomes only | RR 0.93 [0.68, 1.28] | 10 studies · 1722 participants | Moderate |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Erythropoietin plus iron versus control treatment including placebo or iron for preoperative anaemic adults undergoing non‐cardiac surgery 2020 · Cochrane Headline outcomes only | Not reported | Not extracted | Not assessed |
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.