Reduction in level of contamination by particles >5 um (droplets) at <2 m from patient's oral cavity · Dental patients undergoing aerosol-generating procedures (AGPs) and the dental healthcare providers treating them
Chlorhexidine (CHX) led to lower reduction in level of contamination by particles >5 um (droplets) at… compared with saline; GRADE not reported.
2 findings from 1 review
MD -668.4 [-1044.45, -292.35]
1 study · 20 participants
GRADE not reported
MD -21.33 [-36.8, -5.86]
1 study · 12 participants
Very low
Reduction in level of contamination by particles >5 um (droplets) at <2 m from patient's oral cavity · Dental patients undergoing aerosol-generating procedures (AGPs) and the dental healthcare providers treating them
It is very uncertain whether chlorhexidine (CHX) changes reduction in level of contamination by particles >5 um (droplets) at… compared with boric acid (very low certainty).
2 findings from 1 review
MD -8.03 [-9.65, -6.41]
1 study · 60 participants
Very low
MD -26.6 [-28.24, -24.96]
1 study · 60 participants
Very low
Reduction in level of contamination by particles >5 um (droplets) at <2 m from patient's oral cavity · Dental patients undergoing aerosol-generating procedures (AGPs) and the dental healthcare providers treating them
It is very uncertain whether chlorhexidine (CHX) changes reduction in level of contamination by particles >5 um (droplets) at… compared with povidone iodine (very low certainty).
2 findings from 1 review
Reduction in level of contamination by particles <=5 um (droplet nuclei) at >=2 m from patient's oral cavity · Dental patients undergoing aerosol-generating procedures (AGPs) and the dental healthcare providers treating them
It is very uncertain whether chlorhexidine (CHX) changes reduction in level of contamination by particles <=5 um (droplet… compared with ozonated water (very low certainty).
2 findings from 1 review
Reduction in level of contamination by particles >5 um (droplets) at <2 m from patient's oral cavity · Dental patients undergoing aerosol-generating procedures (AGPs) and the dental healthcare providers treating them
1 finding from 1 review
At operator level, because of high heterogeneity (I2 = 89%), which could not be explained, the results were not meta-analysed (2 studies, 60 participants; Feres 2010, Retamal-Valdes 2017). No pooled estimate or GRADE…
2 studies · 60 participants
GRADE not reported
Elevated mutans streptococci levels (>=4 with caries screen; high vs low) · Children and adolescents below 18 years at study start (included studies: children from birth to 15 years), with mixed, permanent or…
It is very uncertain whether chlorhexidine varnish (10%) changes elevated mutans streptococci levels (>=4 with caries screen; high vs… compared with placebo or no treatment (very low certainty).
1 finding from 1 review
Chlorhexidine oral product (one formulation/concentration) vs Another chlorhexidine formulation, concentration or application frequency
Outcome not reported · Children and adolescents below 18 years at study start (included studies: children from birth to 15 years), with mixed, permanent or…
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
0 studies
No studies found
Plaque · Medically healthy individuals (adults and children, 6-60 years)
0.2% chlorhexidine rinse reduced plaque relative to baseline; not GRADE-rated.
1 finding from 1 review
Marginal bleeding · Adults with dental implants and peri-implant mucositis at baseline
Subgingival chlorhexidine irrigation led to lower marginal bleeding compared with chlorhexidine mouthwash; GRADE not reported.
1 finding from 1 review
Plaque · Adults with dental implants and peri-implant mucositis at baseline
Subgingival chlorhexidine irrigation led to lower plaque compared with chlorhexidine mouthwash; GRADE not reported.
1 finding from 1 review
Adverse events · Adults (>18 years) having permanent tooth extraction (predominantly mandibular third molars)
1 finding from 1 review
Presence of dry socket · Adults (>18 years) having permanent tooth extraction (predominantly mandibular third molars)
Chlorhexidine gel (0.2%, intrasocket) showed no clear difference in presence of dry socket compared with chlorhexidine rinse (0.12%) (low certainty).
1 finding from 1 review
Plaque · Medically healthy individuals (adults and children, 6-60 years)
0.12% chlorhexidine rinse reduced plaque relative to baseline; not GRADE-rated.
1 finding from 1 review
Cariogenic bacteria (Mutans streptococci) · People undergoing orthodontic treatment (any age; 9 to 34 years in included studies)
Chlorhexidine mouthwash reduced Mutans streptococci versus placebo, but certainty is very low.
1 finding from 1 review
Cariogenic bacteria (Mutans streptococci) · People undergoing orthodontic treatment (any age; 9 to 34 years in included studies)
Chlorhexidine mouthwash reduced Mutans streptococci versus blank control, but certainty is very low.
1 finding from 1 review
Plaque index (PI) / oral hygiene · People undergoing orthodontic treatment (any age; 9 to 34 years in included studies)
Chlorhexidine mouthwash reduced Plaque Index versus placebo, but certainty is very low.
1 finding from 1 review
Surgical site infection · women undergoing caesarean section
Chlorhexidine gluconate probably leads to lower surgical site infection compared with povidone iodine (moderate certainty).
1 finding from 1 review
Endometritis · women undergoing caesarean section
Chlorhexidine gluconate showed no clear difference in endometritis compared with povidone iodine (low certainty).
1 finding from 1 review
Length of stay · women undergoing caesarean section
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Adverse events (maternal) ‐ skin irritation or allergic skin reaction · women undergoing caesarean section
It is very uncertain whether chlorhexidine gluconate changes adverse events (maternal) ‐ skin irritation or allergic skin reaction compared with povidone iodine (very low certainty).
1 finding from 1 review