Question · asked by 1 review

Chlorhexidine mouthwash vs placebo: Plaque index (PI) / oral hygiene

Population
People undergoing orthodontic treatment (any age; 9 to 34 years in included studies)
Intervention
Chlorhexidine mouthwash
Comparison
placebo
Outcome
Plaque index (PI) / oral hygiene

Chlorhexidine mouthwash reduced Plaque Index versus placebo, but certainty is very low.

What each review found

Include earlier review versions
FindingEffectStudiesGRADE certainty
Chlorhexidine mouthwash vs Placebo
Plaque Index · Orthodontic patients · ≤ 3 months
Chlorhexidine mouthwash reduced Plaque Index versus placebo, but certainty is very low.
The efficacy of mouthwashes on oral microorganisms and gingivitis in patients undergoing orthodontic… (2023) All outcomes
Plaque Index was significantly reduced compared to placebos according to two studies [20; 32].2 studiesVery low

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
The efficacy of mouthwashes on oral microorganisms and gingivitis in patients undergoing orthodontic treatment: a systematic review and…
2023 All outcomes
16 April 2022 (databases and grey literature searched by 16 April 2022; no publication-year limit)47Low / Moderate
How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.